Tyrosine: Precursor of Thyroid Hormones

by Kevin Ahern, PhD

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    About the Lecture

    The lecture Tyrosine: Precursor of Thyroid Hormones by Kevin Ahern, PhD is from the course Amino Acid Metabolism. It contains the following chapters:

    • Tyrosine is a Precursor of Thyroid Hormones
    • Tyrosine Metabolism

    Included Quiz Questions

    1. They include thyroxine and triiodothyronine
    2. They are made inside of thyroid cells
    3. They are made from a precursor derived from tyrosine called thyroglobulin
    4. All of the answers are correct
    5. None of the answers are correct
    1. All of the answers are true
    2. All deiodinases contain selenium
    3. Triiodothyronine, with three iodines, is the most active form
    4. Iodide ion is imported into thyroid cells from the bloodstream
    5. None of the answers are true
    1. All of the answers are true
    2. It is a factor in phenylketonuria
    3. It is treated by reducing intake of phenylalanine and tyrosine
    4. It can result in black urine disease
    5. None of the answers are correct
    1. Tyrosine
    2. Phenylalanine
    3. Methionine
    4. Selenocysteine
    5. Lysine
    1. Deiodinase
    2. Tyrosine transaminase
    3. Aromatic acid decarboxylase
    4. Dopamine-β-hydroxylase
    5. 4-fumaryl acetoacetase
    1. Alkaptonuria is a rare inherited genetic disorder in which the body breaks the tyrosine at very rapid rates and leads to the accumulation of fumarate and acetoacetate in the body
    2. Thyroglobulin protein participates in the synthesis of T4 and T3 hormones in the thyroid gland
    3. The treatment of tyrosinemias and phenylketonuria involves the restriction of intake of amounts of tyrosine and phenylalanine in the individual’s diet
    4. Iodide ions, essential for the production of thyroid hormones, are grabbed from the blood and transported into the thyroid follicular cell via sodium-iodide symport
    5. There are two types of iodine-containing thyroid hormones: triiodothyronine (T3) and thyroxine (T4)
    1. Phenylketonuria—4-Fumarylacetoacetase deficiency
    2. Tyrosinemia II—Tyrosine transaminase deficiency
    3. Tyrosinemin I—4-Fumarylacetoacetase deficiency
    4. Tyrosinemin III—p-Hydroxyphenylpyruvate dioxygenase deficiency
    5. Alcaptonuria—Homogentisate oxidase deficiency

    Author of lecture Tyrosine: Precursor of Thyroid Hormones

     Kevin Ahern, PhD

    Kevin Ahern, PhD

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