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Toxicogenic Bacterial Diarrhea

by Carlo Raj, MD
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    00:01 Talk about toxicogenic bacterial diarrhea.

    00:03 So we?re gonna walk into a little bit more detail here where you have water diarrhea but please note that the feces does not contain leukocytes, WBC free. Staph. aureus it's so ridiculously quick within 6 hours, mayo, mayonnaise at room temperature don?t ever do that.

    00:20 Put your mayo back in the fridge. Also, egg products.

    00:25 So this will obviously refers to mayo and we talked about potato salad which also has the mayo in it.

    00:31 That?s the common denominator. Clostridium perfringens, here rewarming up a precooked food ?Church Picnic Diarrhea.? E. coli travere diarrhea plasma mediated and rehydration absolutely required and maybe perhaps your cotrimoxazole (the combination of sulfomethoxazole and trimetoprim).

    00:53 With E. coli, I remember there?s a huge rage. If it?s E. coli O157:H7, that then brings about undercooked beef and you?re thinking about your hemolytic uremic syndrome in that young child, correct? Whereas if it?s E. coli and you?re dealing with what?s known as ST and LT, and that?s the one in which it is heat stable in which it?s ST and that ST is going to be dealing with your cyclic GMP where as if it?s LT and it?s dealing with cyclic AMP and those are things that you paid attention to earlier on in Micro.

    01:27 It might be a good time for you to make sure you?re completely clear with different types of E. coli.

    01:31 ETEC, EHEC, E. coli, 0157:H7. Vibrio cholera once again this is a good one for you to review for sure and here we talked about this being a secretory type of diarrhea.

    01:44 Here, common denominator for all these organisms? no fecal leukocyte and diarrhea is watery.

    01:55 Continue our discussion with no fecal leukocytes would be bacillus.

    02:02 We?ve talked about the rice that?s been reheated, also tacos.

    02:05 It doesn?t have to be Asian restaurants, it could also be your Mexican restaurants, bacillus.

    02:11 Clostridium botulinum, well, let?s say that you have a child that ends up developing, consumes Clostridium botulinum, spores.

    02:22 Now, the problem is the child, the baby can?t handle the botulinum and so therefore it behaves like botox in a baby.

    02:30 You?ve heard about Floppy Baby Syndrome, haven?t you? That exactly what happens.

    02:34 The botox in an adult, obviously as an adult, our immune system and immune status is competent, so therefore, we don?t have all flaccid paralysis of our entire body, right? But if it?s a baby, my goodness, I mean the botulinum is going to affect the neuromuscular junction in a baby resulting in floppy baby.

    02:56 C. diff. antibiotic associated, hospital setting, 65-70% of diarrhea oftentimes in a hospital setting is because of C. diff. because of antibiotic use.


    About the Lecture

    The lecture Toxicogenic Bacterial Diarrhea by Carlo Raj, MD is from the course Small and Large Intestine Diseases.


    Included Quiz Questions

    1. Staphylococcus aureus
    2. E.coli
    3. Vibrio parahemolyticus
    4. Vibrio cholerae
    5. Clostridium perfringes
    1. Clostridium perfringes
    2. Staphylococcal aureus
    3. Clostridium botulism
    4. Vibrio cholerae
    5. Bacillus cereus
    1. Plasmid
    2. Plasma membrane
    3. Capsule
    4. Pili
    5. Cytoplasmic inclusions
    1. Neurotoxin
    2. Hemotoxin
    3. Lymphotoxin
    4. Myelotoxin
    5. Myotoxin
    1. Cyclic GMP
    2. Cyclic AMP
    3. IP3
    4. DAG
    5. Ca+ ions
    1. Vibrio cholerae
    2. Shigella
    3. Salmonella
    4. Bacillus cereus
    5. Clostridium difficle
    1. Bacillus cereus
    2. E. coli
    3. Salmonella
    4. Shigella
    5. Vibrio Cholerae

    Author of lecture Toxicogenic Bacterial Diarrhea

     Carlo Raj, MD

    Carlo Raj, MD


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