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Structure of Antibodies and Immunoglobulin Domains – Humoral Immunity

by Peter Delves, PhD
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    About the Lecture

    The lecture Structure of Antibodies and Immunoglobulin Domains – Humoral Immunity by Peter Delves, PhD is from the course Humoral Immunity and Cell-Mediated Immunity. It contains the following chapters:

    • The Structure of Antibodies
    • Immunoglobulin Domains
    • Immunoglobulin Domains

    Included Quiz Questions

    1. IgA
    2. IgM
    3. IgG
    4. IgD
    5. IgE
    1. Light chains are attached to heavy chains with H+ bonds
    2. Made of two Fab regions and one Fc region
    3. Heavy chains are held together by disulfide bonds
    4. Approximate size is 150kDa
    5. Has a variable region and a constant region
    1. Kappa
    2. Mu
    3. Delta
    4. Gamma
    5. Epsilon
    1. IgM heavy chains- 4 constant regions
    2. Light chains- 2 constant regions
    3. IgA heavy chains- 2 constant regions
    4. IgE heavy chains- 3 constant regions
    5. IgD heavy chains- 4 constant regions
    1. Are present on the constant region of both light and heavy chains
    2. Hypervariability
    3. Have amino acids that compliment the amino acid sequences in the antigen
    4. Six CDRs are present in each antigen binding site
    5. Three subdivisions of CDRs: CDR1, CDR2, and CDR3

    Author of lecture Structure of Antibodies and Immunoglobulin Domains – Humoral Immunity

     Peter Delves, PhD

    Peter Delves, PhD


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