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Polyp-Cancer Sequence

by Kevin Pei, MD
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    About the Lecture

    The lecture Polyp-Cancer Sequence by Kevin Pei, MD is from the course General Surgery.


    Included Quiz Questions

    1. APC --- K-ras --- TP53
    2. APC --- TP53 --- K-ras
    3. K-ras --- TP53 --- APC
    4. K-ras --- APC --- TP53
    5. TP53 --- APC --- K-ras
    1. APC gene mutation; tumor progression
    2. K-ras mutation alone; colon cancer
    3. K-ras mutation following APC gene mutation; hyperplastic syndrome
    4. DDC gene deletion; tumor suppression
    5. P53 mutation; apoptosis of deleterious cells
    1. A patient has three relatives with colon cancer over two successive generations, one of which was diagnosed at the age of 35.
    2. A patient has two relatives with colon cancer over two successive generations, both of which were diagnosed before the age of 50.
    3. A patient has three relatives with colon cancer over three successive generations, all of which were diagnosed after the age of 65.
    4. A patient has three relatives with colon cancer over three successive generations, all of which were diagnosed before the age of 50.
    5. A patient has 1 relative with colon cancer over two generations, who was diagnosed at the age of 74.
    1. A patient with a family history of mother with endometrial cancer, two cousins with non familial adenomatous polyposis colon cancer who were both diagnosed before the age of 50.
    2. A patient with a family history of grandfather with colorectal cancer and a brother with renal cancer diagnosed at the age of 48.
    3. A patient with a family history of mother, grandmother, and sister all affected by breast cancer before the age of 60.
    4. A patient with a family history of two brothers and a father all with familial adenomatous polyposis colon cancer.
    5. A patient with a family history of a grandfather with colorectal cancer diagnosed at the age of 68, a brother with small bowel cancer diagnosed at the age of 52, and a third cousin with lung cancer diagnosed at the age of 48.
    1. ...prostate cancer.
    2. ...small bowel cancer.
    3. …endometrial cancer.
    4. ...ureter cancer.
    5. ...renal pelvis cancer.
    1. Colorectal carcinoma with high microsatellite instability astrologically diagnosed in a patient less than 50 years old.
    2. Colorectal carcinoma diagnosed in a patient who is less than 50 years old.
    3. The presence of synchronous or metachronous colorectal carcinoma or other Lynch syndrome-associated tumors.
    4. Colorectal carcinoma diagnosed in one or more first-degree relatives with a Lynch syndrome-associated tumor.
    5. Colorectal carcinoma diagnosed in two or more first-degree or second-degree relatives with Lynch syndrome-associated tumors, regardless of age.

    Author of lecture Polyp-Cancer Sequence

     Kevin Pei, MD

    Kevin Pei, MD


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