Quickly, what does Nikolsky sign mean?
The risk or tendency of the
keratinocytes to separate.
If it’s positive, is that a
good thing or bad thing?
When is the last time you want to scrape
your skin and it comes right off?
It’s a bad thing.
So now, you tell me, which
one was the vulgar disease?
That’s the one in which it would
then be positive Nikolsky sign.
What do we call this medically?
What if you don’t see the term Nikolsky?
Then you’ll hear the term achantolysis.
Allow the name to speak to you.
Lysis of your keratinocyte.
Pressure is placed on the blister
or the skin at question.
If the blister spreads laterally, then
Nikolsky sign, obviously, is positive.
If it doesn’t, then it’s negative.
If it is positive, then you
know it’s pemphigus vulgaris.
If it’s negative, then high in your
differential is bullous pemphigoid,
and make sure that you take a
full history of your patient.