Multiple Sclerosis (MS) and Guillain-Bárre Syndrome (GBS)

by Peter Delves, PhD

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    About the Lecture

    The lecture Multiple Sclerosis (MS) and Guillain-Bárre Syndrome (GBS) by Peter Delves, PhD is from the course Hypersensitivity and Autoimmune Disease. It contains the following chapters:

    • Multiple Sclerosis
    • Guillain-Barré Syndrome
    • Myasthenia Gravis

    Included Quiz Questions

    1. 25 %
    2. 1 %
    3. 5 %
    4. 10 %
    5. 50 %
    1. Th1 and Th2 cells that lead to the degradation of myelin and anti-myelin autoantibodies.
    2. Deposition of anti-myelin autoantibodies into brain tissue.
    3. Infiltration of pathogens (bacteria, viruses) which leads to a damaging immune clearing response.
    4. Autoantibodies against glycoproteins in the body to affect CNS glycoproteins.
    5. Increased inflammation and intracranial pressure.
    1. Damaging/destroying ACh receptors as well as autoantibodies that block the remaining receptors.
    2. Inhibition of release of ACh.
    3. Blockage of ACh receptors by autoantibodies to ACh.
    4. Stimulatory autoantibody effect on ACh receptor that results in muscle fatigue.
    5. Autoantibodies against the up- and down-regulating mechanisms of the ACh receptor.

    Author of lecture Multiple Sclerosis (MS) and Guillain-Bárre Syndrome (GBS)

     Peter Delves, PhD

    Peter Delves, PhD

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