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Monoclonal Antibodies and Nonspecific Immunotherapy

by Peter Delves, PhD
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    About the Lecture

    The lecture Monoclonal Antibodies and Nonspecific Immunotherapy by Peter Delves, PhD is from the course Tumor Immunology. It contains the following chapters:

    • Harnessing the Immune System to Attack Tumors
    • Nonspecific Immunotherapy
    • Monoclonal Antibodies
    • Adoptive Cell Transfer

    Included Quiz Questions

    1. CD25
    2. CD20
    3. CD30
    4. GD2
    5. RANKL
    1. Non-Hodgkin Lymphoma
    2. Melanoma
    3. Karposi Sarcoma
    4. Hairy Cell Leukemia
    5. CML
    1. The monoclonal antibody targets proteins on the cell surface of tumor cells, allowing for more efficient delivery of medication toxic to the cell
    2. Enhances the chemotherapeutic effect by utilizing synergistic drug relationships
    3. The monoclonal antibody allows the chemotactic agent to evade the immune system of the patient
    4. The monoclonal antibody allows the chemotactic agent to be taken up by Dendritic cells, causing activation of T cells that target the tumor
    5. The monoclonal antibody induces antibody production by host plasma cells
    1. More efficient tumor antigen recognition with addition of gene sequences that will aid in the destruction of tumor cells
    2. Proliferation of the patient's own T lymphocytes
    3. More efficient delivery of chemotherapeutic agents
    4. Up-regulation of CD8+ T cells and complement activation
    5. Production of monoclonal antibodies by the patient's own immune system

    Author of lecture Monoclonal Antibodies and Nonspecific Immunotherapy

     Peter Delves, PhD

    Peter Delves, PhD


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