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Types of Ovarian Tumors: Maturing Teratoma

by Carlo Raj, MD
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    Let’s go ahead and talk about that mature teratoma. A cystic neoplasm made up of tissue elements from two or more embryonic layer. In other words, we’re talking about a tumor in which it’s a driving your different germ layers, mesoderm, ectoderm, endoderm. You can see skin, hair, bone, all kinds of issues. The most common type of germ cell tumor in a female. Female. The most common germ cell tumor in a male, once again, I sound like a broken record, seminoma. Also known as dermoid cyst. I would know both names, absolutely know both names. A mature teratoma in a female tends to be benign whereas teratoma in a male will be malignant. That’s important. What does that mean? Next step of management. If it’s a teratoma that you would find in a testicle, you just resect it. That’s your next step, surgery, resection. Do not waste time conducting further investigation. Whereas if with the female, maybe perhaps you want to do grading. So there is a little bit of followup and such as necessary. 10 to 15% of these tend to be bilateral. 1% may then go onto malignant transformation. Usually, it will be squamous cell cancer. The subtypes of teratoma will contain only thyroid. That’s interesting. Our topic here, we did endocrinology and we did thyroid. There is struma ovarii. So you have a teratoma here. T – teratoma – will produce T3, T4. Notice I did not say TSH. So there might be actual thyroid tissue in the ovarian teratoma, directly producing T3 or T4. You tell me, does that behave like primary or secondary hyperthyroidism? Very good. Primary. If it’s a directly producing T3 and T4 with struma ovarii, you’d expect the TSH levels to be low, just as you would with primary. Always...

    About the Lecture

    The lecture Types of Ovarian Tumors: Maturing Teratoma by Carlo Raj, MD is from the course Ovarian Diseases.


    Included Quiz Questions

    1. Immature teratoma
    2. Mature teratoma
    3. Dermoid cyst
    4. Struma ovarii
    5. Cystic adenoma
    1. It is always unilateral.
    2. It behaves like secondary hyperthyroidism.
    3. T3/T4 levels are likely to be decreased.
    4. TSH levels are likely to be elevated.
    5. It is a type of epithelial cell tumor.
    1. In men, they are most often benign.
    2. 1% will undergo malignant transformation, usually squamous cell carcinoma.
    3. In women they are most often benign.
    4. They contain at least 2 embryonic layers.
    5. 10-15% are bilateral.

    Author of lecture Types of Ovarian Tumors: Maturing Teratoma

     Carlo Raj, MD

    Carlo Raj, MD


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