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Invasive Bacterial Diarrhea

by Carlo Raj, MD
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    <i>Shigella</i> Bloody diarrhea, bacteremia, Ampicillin resistant strains could be treated with Chloramphenicol. Chloramphenicol pretty much avoided in the US. However, Chloramphenicol, extremely common to be administered in the developing world. Keep that in mind, that's important. You will get a question on Chloramphenicol and some ways they perform. You've heard of Gray baby syndrome. You've heard of Aplastic anemia. And Chloramphenicol, even to this day, developing countries Chloramphenicol extremely common. <i>Salmonella </i> We have the <i>S. typhimurium</i>, most common in the US associated with poulty. Treatment Mild symptoms and ultimately we have Cipro. <i>V. parahemolyticus</i>, ingestion of undercooked shellfish as I mentioned earlier. Antibiotic may or may not be of value. And we have the E. coli or EHEC, hemorrhagic. And at this point I would think that you have O157:H7 memorized, undercooked beef is what you're thinking about. Bloody diarrhea and, in a child, Hemolytic Uremic Syndrome. Uremia to you should mean renal failure. In a child, next step of management, my goodness, you choose hemodialysis with antibiotic at the same time. Hemodialysis, next step of management. HUS, forevermore? Thank goodness, no. You kill off the bacteria in the child and the child comes back perfectly normal. That always makes me happy and when a child gets sick it's not nice. Antibiotic therapy not necessarily effective, hence, the hemodialysis. <i>Staph. aureus</i> Here we have extremely rapid, rapid, rapid type of diarrhea that we talked about. Enterocolitis with positive stool culture. <i>Yersinia enterocolitica </i> Chronic enteritis can mimic your Crohn's, could be associated with Ankylosing spondylitis. Treatment here is your Cotrimethoxazole. <i>Campylobacter jejuni</i> Extremely common and mimics, once again, your Ulcerative colitis. We have<i> Vibrio vulnificus</i>, raw shellfish or wound infection. I was talking to you about this earlier when I was referring to the Gulf. So...

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    The lecture Invasive Bacterial Diarrhea by Carlo Raj, MD is from the course Small and Large Intestine Diseases.


    Author of lecture Invasive Bacterial Diarrhea

     Carlo Raj, MD

    Carlo Raj, MD


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