Intraductal Papilloma

by Carlo Raj, MD

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    00:01 Intraductal papilloma: Solitary.

    00:04 Found within lactiferous duct or sinus.

    00:07 Picture that for me in your head.

    00:09 You’re by the nipple and then you on to a lactiferous sinus, this is where you would find it.

    00:14 More than 80% will present with spontaneous, unilateral, either serous or bloody nipple discharge.

    00:21 That discharge becomes really important for you.

    00:23 Benign.

    00:25 Rarely more than 1 cm in diameter.

    00:27 Most solitary intraductal papillomas are benign, but if there’s multiple papillomas, then you’d find there to be an increased risk in cancer, you can use the same concept earlier that we used for polyps.

    00:40 Remember familial adenomatous polyps? It doesn’t matter what kind of polyp, but if you have hundreds and thousands of them, you increase the risk of cancer.

    00:48 Here, we have a papilloma, if you have increased number of papilloma, and it’s multiple because usually it’s solitary.

    00:54 Then it is concerning that breast cancer, you’re increased in risk for it.

    01:01 In intraductal papilloma, as you would show in the histologic picture, is that within the lactiferous sinus, you will then find a tumor itself and there’ll be dilation of the duct, intraductal papilloma by the lactiferous sinus.

    01:16 Now because of how close the intraductal papilloma is to the nipple, and this is why it becomes important.

    01:22 If you start having damage to the lactiferous sinus and the duct, of course, right from the nipple, you’re going to have discharges.

    01:32 Either serous or bloody, is that clear? So don’t try to memorize that.

    01:36 I mean understand that if you’re so close to the nipple and you’re causing damage, of course, you’re going to have bloody discharge.

    01:42 80%, remember.

    About the Lecture

    The lecture Intraductal Papilloma by Carlo Raj, MD is from the course Breast Disease.

    Included Quiz Questions

    1. Multiple lesions
    2. Bloody discharge
    3. There is no increase in risk of cancer with any of these signs
    4. Lesions > 0.5 cm in diameter
    5. Serous discharge
    1. They are usually located close to the nipple.
    2. They are usually present with multiple lesions.
    3. None of the statements are correct.
    4. They are usually > 1 cm in diameter.
    5. Less than 20% of patients present with nipple discharge.

    Author of lecture Intraductal Papilloma

     Carlo Raj, MD

    Carlo Raj, MD

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