Playlist
Show Playlist
Hide Playlist
Influenza Treatment – Antiviral Drugs
-
Slides Anti-Virals Antimicrobials.pdf
-
Download Lecture Overview
00:00 The next agent I want to talk to you about in terms of influenza treatment is zanamivir. 00:08 These are neuraminidase inhibitors. 00:11 They act by cleaving sialic acid residues. 00:15 Now they prevent clumping of newly released virions. 00:19 So normally when viruses are being released or virions are being released, they clump together and we don't want that to happen. 00:27 Now these agents are inhibiting the neuraminidase. 00:31 So what happens is that the viruses aren't able to spread out. 00:36 Now these are active against both influenza A and influenza B. 00:40 And they're actually also each H1N1 influ. 00:44 If you remember that made some headlines a few years ago. 00:47 It's also active against H3N2 influenza virus as well. 00:54 Worldwide resistance is actually quite rare. 00:57 And we think that the worldwide resistance that does develop is due to mutations of the neuraminidases.
About the Lecture
The lecture Influenza Treatment – Antiviral Drugs by Pravin Shukle, MD is from the course Antimicrobial Pharmacology. It contains the following chapters:
- RNA Polymerase Agents
- Vidarabine & Fomivirsen
Included Quiz Questions
Which is inhibited by zanamivir?
- Viral release
- Penetration
- Uncoating
- Early protein synthesis
- Nucleic acid synthesis
Which agent does not require dose adjustment in renal failure?
- Rimantadine
- Amantadine
- Zanamivir
- Oseltamivir
- Peramivir
Author of lecture Influenza Treatment – Antiviral Drugs
Pravin Shukle, MD
Customer reviews
5,0 of 5 stars
| 5 Stars |
|
5 |
| 4 Stars |
|
0 |
| 3 Stars |
|
0 |
| 2 Stars |
|
0 |
| 1 Star |
|
0 |
