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Hydrolysis – Carboxylic Acids and Their Derivatives

by Adam Le Gresley, PhD
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    The lecture Hydrolysis – Carboxylic Acids and Their Derivatives by Adam Le Gresley, PhD is from the course Organic Chemistry.


    Included Quiz Questions

    1. Deoxyribonucleic acid (DNA)
    2. N,N'-Dicyclohexylcarbodiimide (DCC)
    3. Diisopropylcarbodiimide (DIC)
    4. N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)
    5. 2-Propanephosphonic acid anhydride (T3P)
    1. …formation of soaps from the fatty acids.
    2. …formation of soaps from the carboxylic acid amides.
    3. …formation of soaps from acid anhydrides.
    4. …formation of soaps from acyl chlorides.
    5. …formation of soaps from carboxylic esters.
    1. RCOCl > RCOOCOR > RCOOR > RCONH2
    2. RCOOCOR > RCOOR > RCONH2 > RCOCl
    3. RCOOR > RCONH2 > RCOCl > RCOOCOR
    4. RCONH2 > RCOOR > RCOOCOR > RCOCl
    5. RCOOR > RCOOCOR > RCOCl > RCONH2
    1. Carboxylic acid derivates do not give hydrolysis reactions.
    2. Acyl chlorides and carboxylic acid anhydrides readily undergo hydrolysis to yield carboxylic acids.
    3. The hydrolysis of acyl chlorides, acid anhydrides and carboxylic esters requires acid or base as a catalyst.
    4. Acid amides require stronger acid or base catalysts at elevated reaction temperatures.
    5. Hydrolysis reaction of carboxylic acid derivatives follows addition-elimination reaction.

    Author of lecture Hydrolysis – Carboxylic Acids and Their Derivatives

     Adam Le Gresley, PhD

    Adam Le Gresley, PhD


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