Self-monitoring of glucose, important, all
diabetic should be given a glucometer.
Essential for taking... because once you’re
given insulin, you’re always worried about
your patient going to hypoglycemia.
Self-monitoring, well, what about HbA1C lab
This is a lab test that is conducted so that
you can measure your hypoglycemia.
What does it mean?
It means that the glucose is then going to
bind to haemoglobin by process known as glycosylation.
You’ve heard of that before, but you’ve
heard of that before when we talked about
pathogenesis of diabetes with non-enzymatic
glycosylation where glucose there is binding
to protein causing capillary damage.
What is glucose binding to here and how do
you as a doctor measure your glucose?
When it binds to haemoglobin.
Haemoglobin A1C measures glycemic control
over a period of for the most part an average
lifespan of an RBC which is 120 days or four
May be misleading condition which after an
RBC longevity such as aplastic anaemia and
Now, these are conditions that are sort of
integration point here is the fact that may
Meaning to say that now, when you have aplastic
or chronic haemolysis, then you’re going
to have rapid destruction of that RBC and
so, therefore, may actually show increased
HbA1C, keep that in mind.
They like that question only because it’s
integrating the pharmacology and laboratory