Okay, let's go on to some questions. H2D2, these are not the drugs you are looking for.
Now, if you don't get the joke, you probably have a social life. Let's move on to the question.
The following statements pertain to H2 blockers. Pick the false statement.
A, the H2 blockers are more potent and more effective than the antacids.
B, they irreversibly inactivate the hydrogen potassium ATPase pump.
C, cimetidine has antiandrogenic actions at high doses.
Or D, they inhibit absorption of drugs like ketoconazole.
Remember that H2 blockers do not irreversibly inactivate the hydrogen-potassium ATPase pump.
That distinction lies with the proton pump inhibitors.
Let's move on to another question.
An 80 year old male with chronic constipation
presents with severe gastroesophageal reflux after a large turkey dinner.
The best choice for acute treatment in this individual is?
Aluminium hydroxide? Magnesium hydroxide? Calcium carbonate?
Sodium bicarbonate? Or metoclopramide?
Good, you chose magnesium hydroxide.
So when you are looking at these agents, remember that aluminium hydroxide
can be constipating.
This guy already has constipation so maybe it's not a great choice.
Calcium carbonate and sodium bicarb are weaker antacids.
Calcium carbonate is found in Tums for example,
and sodium bicarb is found in a lot of those effervescent tablets that you buy over the counter.
Metoclopramide is a promotility agent, but not an effective antacid.
So it's not treating both problems. The answer here is going to be B, magnesium hydroxide.
It's also called Milk of Magnesia. It has laxative effects, anti-acid effects,
and it's also quite soothing on the elderly bowel.