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Clostridium Difficile Colitis

by Carlo Raj, MD

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    00:00 Infections of a GI continuum Pseudomembranous colitis is the complication of the bacteria, C. diff. Meaning to stay in a hospital setting, the patient was given antibiotics. All the competitors for C. diff were killed off. The bacteria that ends up on top of the mountain is your C. diff causing Pseudomembranous colitis. Diarrhea; fever; leukocytosis; complications you are worried about, megacolon and perforation. And so therefore colonoscopy shows pseudomembranes, your diagnosis based on toxin assay. The treatment for C. diff would in fact be oral vanco. Recurrence in 25% requires prolonged antibiotics for Clostridium difficile, is our topic. Let's get and take a look at that Pseudomembranous colitis and if you were to then take a look at the colon here, you would notice here that it looks like you are a pseudomembrane and it perhaps looks like also had a colitis in company but it's not, it's a pseudomembrane.


    About the Lecture

    The lecture Clostridium Difficile Colitis by Carlo Raj, MD is from the course Small and Large Intestine Diseases: Basic Principles with Carlo Raj.


    Included Quiz Questions

    1. Abnormally large dilated bowel loops
    2. Twisted bowel
    3. Diverticular shadow
    4. Multiple polypoidal masses
    5. A nodule-like area at the junction of the pylorus and the 1st part of the duodenum
    1. Clostridium difficile
    2. Vibrio cholerae
    3. E. coli
    4. Salmonella typhae
    5. Botulinum toxin
    1. Surgical resection is the treatment of choice.
    2. Antibiotics kill all other competitive bacteria and allow Clostridium difficile to form pseudomembranes.
    3. Colonoscopy biopsy aids in diagnosis.
    4. Bacterial toxin assay aids in diagnosis.
    5. Prolonged usage of antibiotics causes the condition.

    Author of lecture Clostridium Difficile Colitis

     Carlo Raj, MD

    Carlo Raj, MD


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