Clinical Anatomy of Breast Cancer

by Carlo Raj, MD

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    I told you earlier that I would walk you through the clinical anatomy of breast cancer. On the left is your nipple and as you move from the nipple all the way down to stroma, we’ll take a look at various pathologies underneath. With the nipple, two major issues that could occur. You can have Paget’s disease or you could have acute mastitis. Acute mastitis, you might have an abscess formation. If there’s abscess formation, close your eyes, what does the breast look like in a female there? The center area might be a little bit yellowish and purulent and the surrounding tissue, inflammatory, will be erythematous. Then you have Paget’s disease of the nipple. And we’ll talk about that in greater detail. We have to. This is mammary type, obviously. From your nipple, you’ll then move into lactiferous sinus. The major pathology that we discussed in lactiferous sinus thus far is intraductal papilloma. Would you please take a look at how close your lactiferous sinus is to the nipple. So therefore any lesion or pathology to the sinus is then going to result in -- 80% of your patient, what kind of discharge? Bloody or serous. You could also have the mastitis that may affect this area as well, but superficially. Superficially. After this, we’ll get into our ducts. You have a big major and you have a little terminal duct. Group them together, please. And you call them ductal. In the previous discussion, we began with malignancy. We looked at ductal carcinoma in situ. That means that the ducts here, if they undergo cancerous change with maybe ductal hyperplasia and specifically I told you about comedocarcinoma that the basement membrane is going to be intact. But that’s where you’d find your ductal carcinoma in situ. And then if...

    About the Lecture

    The lecture Clinical Anatomy of Breast Cancer by Carlo Raj, MD is from the course Breast Disease.

    Included Quiz Questions

    1. Fibroadenoma
    2. Acute mastitis
    3. Lipoma
    4. Intraductal papilloma
    5. Paget’s disease of the breast
    1. Acute mastitis
    2. Fibroadenoma
    3. Phyllodes tumor
    4. Comedocarcinoma
    5. Intraductal papilloma

    Author of lecture Clinical Anatomy of Breast Cancer

     Carlo Raj, MD

    Carlo Raj, MD

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