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Chirality – Stereochemistry

by Adam Le Gresley, PhD
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    About the Lecture

    The lecture Chirality – Stereochemistry by Adam Le Gresley, PhD is from the course Chemistry: Introduction.


    Included Quiz Questions

    1. Quartz is a perfect example of an achiral inorganic molecule
    2. Chirality is a geometric property of a molecule, which enables it to rotate the plane-polarized light
    3. Non-superposable mirror images of chiral molecule known as enantiomers, exhibit optical activities
    4. D-amino acid and L-amino acids are the enantiomeric forms of an amino acid
    5. A chiral molecule is characterized by the presence of an asymmetric carbon center responsible for the structural features of organic molecules
    1. …the presence of D-deoxyribose sugar in its structure
    2. …the presence of L-deoxyribose sugar in its structure
    3. …the presence of L-nitrogenous base in its structure
    4. …the presence of D-nitrogenous base in its structure
    5. …the presence of phosphodiester bonds in its structure
    1. The natural amino acids are levorotatory as α-carbon atom exhibits the chirality
    2. The natural amino acids are dextrorotatory as β-carbon atom acts as a chiral center
    3. The amino acids exist as a racemic mixture of L- and D- enantiomers inside living systems
    4. The enzymatic machinery of living systems cannot differentiate between L- and D- forms of amino acids
    5. The amino acids are building blocks for nucleic acids
    1. The preparation of a compound in its one specific enantiomeric form for pharmaceutical purposes
    2. The preparation of a compound as a racemic mixture of its enantiomers for pharmaceutical purposes
    3. The preparation of a compound as a racemic mixture of its enantiomers in the ratio of 2:3 (L-form: R-form) for pharmaceutical purposes
    4. The preparation of a compound as a racemic mixture of its enantiomers in the ratio of 1:2 (L-form: R-form) for pharmaceutical purposes
    5. The preparation of a compound as a racemic mixture of its enantiomers in the ratio of 2:3 (R-form: L-form) for pharmaceutical purposes
    1. …interaction of the drug with its target molecule and drug-metabolizing enzymes
    2. …interaction with water molecules
    3. …interaction with the salts present in the blood plasma
    4. …interaction with the preservatives used in drug preparation
    5. …interaction with O2 and CO2 gases dissolved in the blood

    Author of lecture Chirality – Stereochemistry

     Adam Le Gresley, PhD

    Adam Le Gresley, PhD


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