Blood Vessel and Heart Development

by John McLachlan, PhD

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    Hello, and welcome to this lecture on the development of the heart and blood vessels. Now, I should tell you honestly right to the start that heart development is complicated and difficult to understand. So, you may have to watch this one several times before you grasp it fully. It probably wouldn’t do any harm if you revised the circulation of blood through the adult heart before starting in order to make clear of some of the processes that we’re going to be looking at. However, we can summarize what we’re going to see as we’ll look, first of all, at the formation of the blood cells, then we’ll look at the origin of the early heart, then we’ll look at looping of the heart, and then finally, division of the two-chambered heart into the four chambers of the adult heart, a process known as septation. We’re beginning very early in the embryonic process, not long after gastrulation. Up at the top of the image, you can see the embryo running across the screen. Hanging down from that is the yolk sac. On that yolk sac, little spots of red begin to appear, and these are actually blood islands where red blood cells are differentiating from the mesoderm of the yolk sac. So these are endothelial bags. They are lined with endothelium, and we’ll look at the histology in a second, and each of them contains red blood cells. Gradually, these islands will begin to join up and they form a loose meshwork or net through which blood begins to flow as the heart begins to beat. Where the blood is flowing fastest, there, those turn into major blood vessels. So the formation of the blood vessels is driven by the circulation driven by the heart. So they will flow...

    About the Lecture

    The lecture Blood Vessel and Heart Development by John McLachlan, PhD is from the course Embryology: Advanced. It contains the following chapters:

    • Formation of Blood
    • Early Development of the Heart
    • The Septation of the Heart

    Author of lecture Blood Vessel and Heart Development

     John McLachlan, PhD

    John McLachlan, PhD

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    Fail lecture! …
    By Shayan R. on 25. May 2016 for Blood Vessel and Heart Development

    Fail lecture! He is not a good professor. Change him.