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B-Cell Immunodeficiencies: Common Variable Immunodeficiency, X-linked Agammaglobulinemia and Selective IgA Deficiency – Primary Immunodeficiency

by Peter Delves, PhD
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    About the Lecture

    The lecture B-Cell Immunodeficiencies: Common Variable Immunodeficiency, X-linked Agammaglobulinemia and Selective IgA Deficiency – Primary Immunodeficiency by Peter Delves, PhD is from the course Immunodeficiency and Immune Deficiency Diseases. It contains the following chapters:

    • Examples of Primary Immunodeficiency Affecting B-cells
    • Common Variable Immunodeficiency
    • X-Linked Agammaglobulinemia
    • Selective IgA Deficiency

    Included Quiz Questions

    1. Bruton’s tyrosine kinase
    2. MHC class II
    3. CD19
    4. BAFF
    5. ICOS
    1. Most patients are severely immunocompromised
    2. Circulating IgA and secretory dimeric IgA are affected
    3. Sources of genetic defect are largely unknown
    4. IgM can be transported to mucosal surfaces
    5. Other classes of antibodies compensate for IgA

    Author of lecture B-Cell Immunodeficiencies: Common Variable Immunodeficiency, X-linked Agammaglobulinemia and Selective IgA Deficiency – Primary Immunodeficiency

     Peter Delves, PhD

    Peter Delves, PhD


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