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Asthma Medication Questions

by Pravin Shukle, MD
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    00:01 Let's do some questions. The following are bronchodilators. Prednisone, cromolyn, theophylline, omalizumab, and montelukast.

    00:19 Good, theophylline. Remember that prednisone is a steroid, it is an anti-inflammatory agent, it does not cause bronchodilation.

    00:27 Cromolyn is a mast cell degranulation inhibitor or a release inhibitor.

    00:32 Omalizumab is a IgE mediated monoclonal antibody and montelukast is a leukotriene antagonist.

    00:42 Pick the false statement.

    00:45 Zileuton selectively inhibits lipoxygenase. LT antagonists or LTAs are effective in acute asthma episodes.

    00:54 LTAs are effective in antigen induced bronchospasm. LT agonists have low toxicity.

    01:01 And montelukast is an antagonist of the LTD4 receptor.

    01:07 The false statement is that LT antagonists are effective in acute asthma episodes.

    01:12 Remember that we do not want to use this medication in acute asthma, we want to use it in chronic asthma and it maintains stability.

    01:21 Let's move on to the next question, corticosteroids. So finish the sentence.

    01:29 Corticosteroids reduce the synthesis of arachidonic acid by folic acid reduction.

    01:34 B, corticosteroids increase the expression of COX-2.

    01:40 C, corticosteroids inhibit phospholipase A2 activity to reduce arachidonic acid levels.

    01:47 D, inhaled corticosteroids are rarely used due to systemic side effects.

    01:52 And E, prednisone is commonly used in chronic mild asthma.

    01:59 Right, corticosteroids inhibit phospholipase A2 activity to reduce arachidonic acid levels.

    02:07 Well, there you have it. That's our respiratory lecture. I hope you enjoyed it, I hope you learned something.

    02:12 Good luck on your exams. I'm sure you're going to do really well.


    About the Lecture

    The lecture Asthma Medication Questions by Pravin Shukle, MD is from the course Respiratory Pharmacology.


    Author of lecture Asthma Medication Questions

     Pravin Shukle, MD

    Pravin Shukle, MD


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    Loved this, excellent!
    By Petty K. on 18. June 2017 for Asthma Medication Questions

    Literally shortened my 1hr lecture into 10 mins and covered everything I need!

     
    Very Good!
    By Reymark G. on 22. May 2017 for Asthma Medication Questions

    Good teacher and has a calm voice, makes him a good speaker.