Asbestos, PCB's, Herbicides & Pesticides – Toxic Substances

by Pravin Shukle, MD

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    Asbestos is a common insulator. At one time, it was used almost exclusively as an insulator in the construction industry and you'll be surprised how ubiquitous this product is. I remember as a child, playing in construction yards, I remember playing with asbestos. That's how common it was. It is now banned in most countries. And it's more relevant today in the destruction industry rather than the construction industry. So, if you have a patient, who is involved in destruction of a property or renovation of a property, that was built prior to the 1940s, one of the things you really want to think about is asbestos insulation toxicity. Now, the other thing that I want to mention and is often overlook is when we're reinsulating pipes for plumbing or replacing plumbing pipes, a lot of those plumbing pipes in airdocks were insulated with asbestos on the outside. And so when they're tearing these things out, they release asbestos fibres into the air. The acute symptoms are generally dyspnea or an asthma like syndrome. The long term implication that we worried about is mesothelioma, which is a type of cancer. Polychlorinated biphenyls or PCB's are used in the electrical industry. They're often used in insulation and in wire stripping. They are poorly metabolized and highly persistent in the environment. And they go through what's called predetor concentration. So, it's in small amount in animals that are at the bottom of the food chain, and they concentrate as you get higher and higher in the food chain. Obviously because humans are what we call a top predator, and they concentrate the most in humans. They often remain in the food chain for decades. They are most often associated with the folliculitis and keratosis. Sometimes you can get a corneal keratosis as...

    About the Lecture

    The lecture Asbestos, PCB's, Herbicides & Pesticides – Toxic Substances by Pravin Shukle, MD is from the course Toxicology. It contains the following chapters:

    • Asbestos
    • Polychlorinated Biphenyls
    • Herbicides
    • Pesticides

    Included Quiz Questions

    1. Mesothelioma
    2. Small cell carcinoma
    3. Squamous cell carcinoma
    4. Adenocarcinoma
    5. Focal Nodular Hyperplasia of the liver
    1. Non-Hodgkins Lymphoma
    2. Berkit's lymphoma
    3. Large B cell lymphoma
    4. Neuroblastoma
    5. Paget's Disease
    1. Cholinesterase inhibitor
    2. Muscarinic acetylcholine receptor agonist
    3. Nicotinic acetylcholine receptor agonist
    4. Alpha-1 and Alpha-2 agonist
    5. Chloride channel blocker
    1. Dilated pupils
    2. Pinpoint pupils
    3. Bronchoconstriction
    4. Vomiting
    5. Diarrhea

    Author of lecture Asbestos, PCB's, Herbicides & Pesticides – Toxic Substances

     Pravin Shukle, MD

    Pravin Shukle, MD

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