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Vascular Anatomy – Blood Vessels and Pressure

by Thad Wilson, PhD
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    So let's take mean arterial pressure as our endpoint and go through what are the factors that affect mean arterial pressure. Well, one of the biggest things we've already discussed here is systemic vascular resistance. So the more resistance there is in the tube system, the higher the pressure. If heart rate is higher, you're going to have a higher cardiac output and that will drive pressure to increase. If the heart contracts to a greater extent, if the contractility increases which we call inotropy that will also increase mean arterial pressure. If venous compliance decreases, that will also increase mean arterial pressure. Also, if you increase the volume that's circulating around of the blood, that will increase mean arterial pressure and you usually do that through the renal sodium and water reabsorption or handling. When you go through that process, you get an increase in blood volume. By decreasing venous compliance, you get an increase in preload which is both volume and venous compliance related. If you have an increase in preload, that also increases your stroke volume just like inotropy did. That increase in stroke volume feeds in to an increase in cardiac output just like the increase in heart rate and our final end product here is mean arterial pressure which is affected by the cardiac output and of course systemic vascular resistance. So that is why we can utilize the formula of mean arterial pressure equals or approximates cardiac output times systemic vascular resistance. So when you think about mean arterial pressure, we have to think what are the other determinants of mean arterial pressure. One of the main items to consider is how the circuit is set up and you go circuit circuit. What are we talking about with the circuit? Similar to an electrical...

    About the Lecture

    The lecture Vascular Anatomy – Blood Vessels and Pressure by Thad Wilson, PhD is from the course Vascular Physiology.


    Included Quiz Questions

    1. 5 point serial arrangement
    2. 3 point serial arrangement
    3. 5 point parallel arrangement
    4. 3 point parallel arrangement
    1. Arterioles
    2. Venules
    3. Capillaries
    4. Veins
    1. Capillaries
    2. Aorta
    3. Vena cava
    4. Femoral artery
    5. Brachial artery
    1. Right atrium
    2. Left atrium
    3. Right ventricle
    4. Left ventricle
    5. Great cardiac vein
    1. Veins
    2. Arteries
    3. Arterioles
    4. Capillaries
    5. Aorta

    Author of lecture Vascular Anatomy – Blood Vessels and Pressure

     Thad Wilson, PhD

    Thad Wilson, PhD


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