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Types of Thyroid Carcinoma

by Carlo Raj, MD
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    Thyroid cancer types. Differentiated, papillary, male preponderance peaking between 30 to 50; you should know everything that I will be referring to here with papillary, differentiated. Lymphatic spread versus angioinvasive, this is lymphoinvasive, usually excellent prognosis, thank goodness, because it is common. High incidence in patients with a Gardner’s syndrome, which is familial adenomatous polyposis; young patient with hundreds and thousands of polyps. Along with this, also has sebaceous cysts, skin issues, dull bone pain, osteoma and a desmoid tumor, meaning to say your fibroma, right? Follicular, second most common, female preponderance, slow growth, painless nodules, cold nodules, both would be any type of cancer, this is… invades the capsule in vascular system. Let’s stop here for a second. An adenoma was angioinvasive more so than lymphoinvasive. Papillary cancer, on your left, lymphoinvasive, follicular angioinvasive, but follicular, it will go beyond the capsule whereas adenoma, by definition, well encapsulated. Are we clear? If not, review that point. Angioinvasive, hematogenous; once again, excellent prognosis. Medullary, 10 percent, arises from parafollicular C cells which produces calcitonin and if there is any discussion of amyloid, it will be the calcitonin type. Do not forget that. 20 percent with MEN IIA or IIB, it will be associated with both. We will talk about this in greater detail when we talk about IIA and IIB; both of them will have pheochromocytoma, both of them will have medullary cancer with thyroid, RET, RET, RET, proto-oncogene; good prognosis. I will quickly mention anaplastic, less than 5 percent, poor prognosis, as you can expect with anaplastic; often prior history of goiter or perhaps even papillary thyroid cancer. And the final type that you do want to keep in mind would be lymphoma, less than 5 percent of thyroid cancers, seen associated with, this is important, Hashimoto, autoimmune disease,...

    About the Lecture

    The lecture Types of Thyroid Carcinoma by Carlo Raj, MD is from the course Thyroid Gland Disorders.


    Included Quiz Questions

    1. Papillary carcinoma
    2. Follicular carcinoma
    3. Medullary carcinoma
    4. Anaplastic carcinoma
    5. Lymphoma
    1. Follicular carcinoma
    2. Papillary carcinoma
    3. Medullary carcinoma
    4. Anaplastic carcinoma
    5. Lymphoma
    1. Medullary carcinoma
    2. Papillary carcinoma
    3. Follicular carcinoma
    4. Lymphoma
    5. Anaplastic carcinoma
    1. Lymphoma
    2. Anaplastic carcinoma
    3. Medullary carcinoma
    4. Follicular carcinoma
    5. Papillary carcinoma
    1. Average age- 35
    2. Pathogenesis related to p53 mutation
    3. Follicular epithelial origin
    4. Rapid growth, aggressive
    5. Mortality approaches 100%

    Author of lecture Types of Thyroid Carcinoma

     Carlo Raj, MD

    Carlo Raj, MD


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