Types of Syphilis

by Carlo Raj, MD

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    The secondary syphilis. A couple of things that you very much want to keep in mind with secondary syphilissyphilis that you will not find with primary. First, it’s five weeks after primary lesion. Go in odd numbers. We have three and five. Three weeks after the lesion will be primary. Five weeks after the primary would be secondary. What are you going to find in secondary? Proliferation of spirochete and the skin and the mucous membrane become involved. Skin is huge. And the reason I say skin is in the picture. You’ll find these lesions on the palms and the soles. Secondary syphilis. You will not find this is in primary. Most likely. Moist areas are also where you would find these lesions. You’re thinking about the axilla or anogenital region, and then the mucous membranes include your mouth, the throat, the vagina. All part of your syphilitic secondary type. Primary and secondary, keep them separate. The tertiary would be five years or more after initial infection. So now, the number that you want to know for sure or your area code is 3-5-5. Three weeks for primary. Five weeks after the primary for secondary. Five years after, you then develop tertiary. This is the one that you have probably seen many times in -- Well, we’ve talked about this in cardiology and you’ve also talked about this in neuroscience, with something called tabes dorsalis. When did we talk about this in cardiology? I gave you that murmur in which you’d find the murmurby the third intercostal space, left peristernal. What is that? Remember, please, if the blood vessels are being involved and they’re obliterated, we call this what in tertiary syphilis? Endarteritis obliterans. If you knock out the endarteries of the big aorta, the aorta dies or it becomes...

    About the Lecture

    The lecture Types of Syphilis by Carlo Raj, MD is from the course Sexually Transmitted Diseases (STDs).

    Included Quiz Questions

    1. A generalized mucocutaneous rash, involving palms and soles.
    2. Seizures, delirium, and high grade fever with small red clustered papules on chest, arms and legs.
    3. Generalized tender blisters sparing palms and soles and mucocutaneous junctions
    4. Ulcerated chancres both inside and outside the vagina, with severe pruritis.
    5. Generalized, tender, oozing and bleeding small ulcers, accompanied by low grade fever, and a new murmur on auscultation.
    1. All of these.
    2. Endarteritis obliterans, leading to aortic aneurysm formation
    3. Gummas in skin
    4. Tabes Dorsalis
    5. Gummas in liver and/or bone
    1. Primary syphilis 3 weeks after initial exposure, secondary syphilis 5 weeks after primary lesion, and tertiary syphilis 5 years after initial exposure
    2. Primary syphilis at the time of exposure, secondary syphilis 3 weeks after exposure, and tertiary syphilis 2 years after exposure
    3. Primary syphilis 3 days after exposure, secondary syphilis 5 days after exposure, tertiary syphilis 5 months after exposure
    4. Primary syphilis 3 hours after exposure, secondary syphilis 5 hours after primary lesions, and tertiary syphilis 5 weeks after secondary syphilis
    5. Primary syphilis 3 days after exposure, secondary syphilis 5 months after primary syphilis, and tertiary syphilis 5 months after secondary syphilis
    1. Vertical (trans-placental) transfer
    2. During passage through birth canal
    3. At the time of placental detachment
    4. Breast feeding
    5. Skin to skin contact
    1. It only manifests as a skin rash few hours after birth.
    2. It can manifest in early or late childhood, sometimes even in adulthood
    3. In an infant, it can cause skeletal deformities like anteriorly curved tibias.
    4. It can lead to hepatomegaly and skin rash in infants.
    5. It can be a cause of deafness, blindness, and notched central incisors.

    Author of lecture Types of Syphilis

     Carlo Raj, MD

    Carlo Raj, MD

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