Types of Non Germ Cell Tumors

by Carlo Raj, MD

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    00:02 Our topic here is testicular neoplasia and now we’re moving away from germ cell tumors.

    00:07 These are non-germ cell tumors.

    00:10 I’ll have you focus on the following: If you have a Leydig cell tumor, a Leydig cell tumor would be producing quite a bit of testosterone.

    00:20 And if there’s quite a bit of testosterone being formed, then you have this boy who undergoes precocious puberty.

    00:25 Now, in addition to that, know the clinical presentation.

    00:29 Golden brown color.

    00:31 There’s something called Reinke crystal and these then appear more or less red like or eosinophilic cytoplasmic inclusions.

    00:41 And because of all the testosterone that’s being produced, there’s every possibility that there might be aromatization of the testosterone into estrogen.

    00:49 So now, with estrogen, gynecomastia perhaps in this patient.

    00:54 And I told you with all these androgen and if it’s a young male, might experience precocious puberty.

    01:02 Sertoli cell, call it androblastoma from sex cord stroma.

    01:08 And then you have testicular lymphoma.

    01:10 The most common testicular cancer in older men, that’s important.

    01:14 Know the age groups.

    01:16 Not a primary cancer.

    01:17 Arises from metastatic lymphoma to the testis.

    01:22 Oftentimes, the lymphatics are involved in the testis, extremely common in elderly patients, unfortunately.

    01:29 Pay attention to your age groups.

    About the Lecture

    The lecture Types of Non Germ Cell Tumors by Carlo Raj, MD is from the course Male Reproductive System Diseases.

    Included Quiz Questions

    1. They have a "fried-egg" appearance.
    2. Large quantities of testosterone are produced.
    3. Gynecomastia might occur in men.
    4. Precocious puberty occurs in boys.
    5. Reinke crystals are present.
    1. Leydig cell tumor is a germ cell tumor.
    2. Seminoma is the most common germ cell tumor.
    3. Testicular lymphoma is the most common testicular tumor in older men.
    4. Androblastoma is a Sertoli cell tumor.
    5. Testicular lymphoma is mostly secondary.

    Author of lecture Types of Non Germ Cell Tumors

     Carlo Raj, MD

    Carlo Raj, MD

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