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Leukemia: Types of Leukemia incl. Hairy Cell Leukemia (HCL) and Adult T-Cell Leukemia/Lymphoma (ATLL) – White Blood Cell Pathology

by Carlo Raj, MD
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    Ultimately, this table gives you the highlights of what you need to know for your leukemias. We’ve walked through every single one in great detail, and now at this point, let’s quickly walk through what you need to know from comparing one from the other. Age: Children affected by leukemia, ALL. The oldest patient to be affected with leukemia, CLL. Forties, CML. AML, all over the place, 15 to 60. Onset, acute/acute. What does that mean? In your bone marrow, you'll find greater than 20% blasts. What was that pre-leukemia that I told you about AML? That was myelodysplastic syndrome. Do not forget that. And in RBC pathology, I’d also discussed it. There’s a variant that you want to know known as refractory anemia, a ring sideroblast. Chronicity, well, chronic. You would have less than 10% blast in the bone marrow. CLL associated with SLL, aggressive form, Richter transformation. CML, aggressive fashion. What is that called? Blast crisis. Symptoms, acute: bone, bone, bone pain. That’s what you pay attention to because of infiltration of bone marrow. If it’s chronic, many times, nonspecific but anemia type of symptoms. Prognosis: ALL, excellent. What kind? Pre-B type. Pre-T, a killer. AML, moderate. If you’re dealing with M3, 30% cured, by? ATRA. CML, pretty decent, especially when you can use imatinib. The trade name is Gleevec, the generic name is imatinib. And CLL, poor and slowly progressing, unless it goes into Richter transformation, which is now known as your diffuse large B-cell lymphoma. Here, we have hairy cell leukemia. Allow the name to speak to you. This is once again of B-cell origin but it is rare. Older males, splenomegaly. I’m going to give you the highlights of what you want to take a look at. You want to specifically look for monocytopenia. That...

    About the Lecture

    The lecture Leukemia: Types of Leukemia incl. Hairy Cell Leukemia (HCL) and Adult T-Cell Leukemia/Lymphoma (ATLL) – White Blood Cell Pathology by Carlo Raj, MD is from the course Leukemia – White Blood Cell Pathology (WBC).


    Included Quiz Questions

    1. Acute lymphoblastic leukemia
    2. Acute myeloid leukemia
    3. Hairy cell leukemia
    4. Chronic myeloid leukemia
    5. Chronic lymphocytic leukemia
    1. Acute lymphoblastic leukemia
    2. Chronic lymphocytic leukemia
    3. Acute myeloid leukemia
    4. Acute T-cell leukemia
    5. Hairy cell leukemia

    Author of lecture Leukemia: Types of Leukemia incl. Hairy Cell Leukemia (HCL) and Adult T-Cell Leukemia/Lymphoma (ATLL) – White Blood Cell Pathology

     Carlo Raj, MD

    Carlo Raj, MD


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