Treponema Pallidum and Primary Syphilis

by Carlo Raj, MD

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    00:01 Here we have treponema pallidum.

    00:03 I’ll go through this rather quickly.

    00:04 You’ve gone over this in micro.

    00:06 The salient points that are important for us in pathology include the following: The picture showing you on dark field microscopy a gram-negative spirochete.

    00:14 Now the major spirochete that you absolutely must know for your boards include what? What’s the name of that organism that brings about Lyme’s disease? There you go.

    00:23 Borrelia burgdorferi.

    00:27 The primary lesion, you need to know the time.

    00:30 Let’s make sure we reinforce the time.

    00:32 A primary lesion three weeks after contact.

    00:35 Three weeks after contact, three weeks after contact for primary.

    00:40 And primary, remember, you’ve done the equivalent to a male and on the penis, he would find an ulceration.

    00:47 This is not going to be painful.

    00:49 Not.

    00:50 Why am I emphasizing this? Because it’s important that you review later on what’s known as Haemophilus ducreyi.

    00:58 And there you’d find a chancroid, and that is painful.

    01:02 So when we talk about chancre and chancroid, most of you probably have seen these on the penis, which is most likely what the presentation will be on your boards.

    01:10 However, obviously, these things can also occur in a female.

    01:14 A chancre is painless.

    01:17 Firm, nontender, raised, red lesion.

    01:19 You might find this in the cervix or the vaginal wall.

    01:22 Next, it is a spirochete, and the type of microscopy that you use here in fact is dark field as the picture clearly demonstrates.

    01:31 Heals in three to six weeks even without treatment.

    01:35 Interesting, huh? Now the next topic after this will be --

    About the Lecture

    The lecture Treponema Pallidum and Primary Syphilis by Carlo Raj, MD is from the course Sexually Transmitted Diseases (STDs).

    Included Quiz Questions

    1. After 21 days
    2. After 14 days
    3. After 7 days
    4. After 28 days
    1. It is painless.
    2. It is subcutaneous.
    3. It is in a skinfold.
    4. It is intravaginal in females and intraurethral in males.
    5. It forms and heals within a matter of hours.

    Author of lecture Treponema Pallidum and Primary Syphilis

     Carlo Raj, MD

    Carlo Raj, MD

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