00:02
To identify what history… what disease they
may have, that requires taking a history.
00:06
Now the format of the history for respiratory
disease is the same as the format of the history
for any other medical problem: patient's age,
sex, country of birth, which we've already
discussed. The next question is What is their
main problem? What is their presenting complaint?
And that may be one complaint—breathlessness—or
maybe they've got two: breathlessness with
chest pain. You then need to take a very detailed
history of that presenting complaint. And
this is something that students often fail
to do effectively, is to take a very good
assessment of the history of the presenting
complaint so that you can fully describe what
the patient has been suffering over the past
day, minutes, weeks, months, years (depending
on whether it's a chronic or acute problem).
Past medical history may dictate the problem
that they… respiratory problem that they're
suffering from to a certain extent, so that
needs to be explored. Social history is incredibly
important for respiratory disease, as occupational
and recreational exposures will often lead
to respiratory diseases of very specific types.
01:14
The review of symptoms is something where
you're basically asking the patient whether
they have any other issues which may be affecting
them at the present time, and they're not
terribly important for most respiratory diseases.
Treatment history is where you identify what
medications or drug… and drug therapies
the patient has been using, and that is important
for all assessments—clinical assessments—of
patients.
01:37
So to take the main symptoms that you might
get in respiratory disease: These are breathlessness,
cough, chest pain, wheeze. Those are the main
problems that you might have. Taking dyspnea—shortness
of breath—to start with: This can be caused
by respiratory disease, obviously, but also
by cardiac disease and by anemia, so you need
to think about whether those are present as
well. The important thing about breathlessness
is to define how long the patient has been
breathless for. Whether the breathlessness
has a specific periodicity: Is it constant?
Does it go up and down? Is it variable or
intermittent? And it if it is there the whole
time, is it a problem that's stable or is
it getting worse? Because this feel for what's
happening with the breathlessness will give
you a good idea about what's going on.
02:30
So for example, asthma is an intermittent
cause of breathlessness, whereas COPD will
cause breathlessness the whole time, although
there might be intermittent situations where
it gets worse when you have an exacerbation.
And some diseases—say, if you've had a resection
for lung… for a lung cancer—may leave
you more breathless than before, but that
won't change over time. That would be a stable
breathlessness since the surgery. If the disease
is getting worse, then you need to get a feel
for the speed of progression, because that
will give you a feel for what the underlying
cause is. So, for example, COPD (chronic obstructive
pulmonary disease)—lung damage due to smoking—progresses
slowly over months and years, in general.
03:15
It takes a long time to develop breathlessness
due to COPD. However, if you've got a pleural
effusion, that normally develops over a period
of days and weeks, and so the breathlessness—as
the effusion gets bigger—the breathlessness
will get worse over that sort of period of
time.
And you work this out by assessing the patient's
level of exercise tolerance. So for example,
you can ask the patient, "Okay, you've been
breathless for six months. What does it stop
you from doing?" And the patient may say,
"Well, I can walk to the bus, but that's about
200 yards. But if I try to go to the park,
which is 400 yards, I can't do it." And that
gives you a feel for how breathless they are,
and it also gives you a measure. And you say,
"Okay, a year previously, could you walk to
the park?" And they say, "Yes." That means
that the disease has progressed over that
period of time. By using this assessment of
what the patient can do without getting breathless
and comparing to the past, you get a feel
for whether it's constant, progressive, and
also the level of severity of the problem.
There is an MRC (a medical research council)
scale that's used for breathlessness. I don't
think it's particularly helpful, but it's
important to know about it, as it is used
often in papers and in clinical trials. So
MRC Scale 0 means the patient's not breathless.
Grade 1 means they're dyspneic on climbing
hills and stairs, but they're okay if they're
walking on the flat. Grade 2: Actually walking
on the flat becomes a problem, but only after
walking 1.5 km or thereabouts, and only if
they're... or if they're forced to walk faster
than usual for some reason, i.e. if they're
walking with a friend who hasn't got a problem,
is able to walk a bit faster than them. Grade
3 is where they get breathless on exertion
after walking about 100 m. So they can walk
100 m; then they have to stop to catch their
breath. And Grade 4 is severe breathlessness,
which means they're breathless either at rest
or on doing minimum effort: undressing, moving
from the chair to the toilet, etc. So they're
breathless pretty much the whole of the time.
05:30
So I mentioned before: Speed of onset is important
for breathlessness. So there are a limited
number of causes which cause very rapid deteriorations
in your breathing over a short period of time,
over minutes. A pneumothorax (air in the pleural
space) comes on very suddenly, and that will
be a sudden cause of breathlessness. An occlusion
of the pulmonary arteries—a pulmonary embolus—again,
that's a sudden cause of breathlessness. One
minute the patient is fine; the next, they're
breathless. Other causes which come on over
a period of a few minutes or a few hours is
pulmonary edema, left ventricular failure
with fluid filling up the lungs, and asthma
exacerbations.
Episodic breathlessness: Periods when the
patient is well with no breathlessness intermingled
with periods where they are breathless: That
tends to suggest asthma for respiratory disease,
but it could also be due to heart disease
in the form of ischemic heart disease, where
you get periods of ischemia which make you
feel breathless, but they're normally associated
with chest pain (not always so). And then
hyperventilation is a problem where patients
will be hyperventilating and feeling breathless,
but that's largely an anxiety-related problem
rather than a physiological problem due to
lung disease.
And then there's progressive breathlessness.
06:43
And that could be over a short period of time,
over days or weeks, and that would suggest
a pleural effusion, developing anemia, or
developing a collapse of the lung. So if you've
got a tumor that's blocking a main bronchus,
then slowly over time as that tumor grows,
that bronchus becomes more and more blocked,
and the patient becomes more and more breathless.
07:01
Also occurs with multiple pulmonary emboli,
where small pulmonary emboli are blocking
off individual small arteries over time.
Progression over months or years: That will
be a classical situation for somebody with
chronic obstructive pulmonary disease, chronic
asthma (so that's patients with slowly worsening
asthma leading to airways obstruction over
time). Bronchiectasis potentially can lead
to progressive respiratory impairment over
time. Interstitial lung disease and multiple
pulmonary emboli. You also need to think about
cardiac failure as a potential problem as
well. But the classic situation there with
people presenting with breathlessness over
months is you need to think about COPD if
they're a smoker, and if you hear crackles
in their chest, it's… interstitial lung
disease is the big thing that you need to
consider.