Role of the Liver

by Kevin Ahern, PhD

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    00:00 Now it's important to recognize that the needs of a cell or the reciprocal regulation of a cell is not something that carries its way all the way through the body. And a really good example of this is what I am getting ready to show you here.

    00:13 This is known as the Cori Cycle.

    00:17 The Cori Cycle plays a very important role in helping us to maintain blood glucose But it also shows us the needs of the different parts of the body can be considerably different.

    00:28 When the blood glucose is low, what does the liver do? The liver puts glucose out to maintain those levels. And the liver's role in the body is maintaining levels whether it's of sugars or it's of fatty acids.

    00:41 The liver tries to maintain a stasis, as it were, or a continual level of control.

    00:48 When the blood glucose is high then the body produces insulin and the cell of the body are stimulated to take up glucose from the blood to reduce the concentration of glucose.

    About the Lecture

    The lecture Role of the Liver by Kevin Ahern, PhD is from the course Metabolic Control.

    Included Quiz Questions

    1. The Cori cycle acts as a major source of ATP during the muscle contraction in the anaerobic conditions
    2. The liver senses the blood glucose levels and controls the release of glucose accordingly
    3. The Cori cycle is an important source of substrate for gluconeogenesis and helps in the prevention of lactic acidosis in the muscles under anaerobic conditions
    4. In the lactic acid cycle or Cori cycle, the lactate produced during anaerobic glycolysis in the muscle cells is moved to the liver and converted to the glucose
    5. The insulin hormone stimulates the body cells to take up the glucose from the bloodstream

    Author of lecture Role of the Liver

     Kevin Ahern, PhD

    Kevin Ahern, PhD

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