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Quick Review: Sjögren's Syndrome

by Stephen Holt, MD, MS

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    00:01 Alright, so let's do a quick review.

    00:02 I'll ask some questions, feel free to pause the screen, come up with your own answer, and then unpause the screen and we'll see what we came up with.

    00:10 First off, all of the following are commonly associated with Sjogren's syndrome except: alright, so we talked about the family of autoimmune diseases with Sjogren's syndrome.

    00:24 One of which is definitely Raynaud's phenomenon.

    00:27 Again, along with lupus, scleroderma, and others.

    00:31 Next stop, Hodgkin's lymphoma, I know we said something about Hodgkin's, it was non-Hodgkin's lymphoma, that's the one that's associated with Sjogren's so that's gonna be our answer and by virtue of it being an incorrect choice.

    00:43 Just to round things out, sublingual gland enlargement; definitely a feature of Sjogren's syndrome.

    00:49 Oral thrush as we mentioned, by virtue of having a dry mouth and not having saliva.

    00:54 And then the dental caries along the same lines.

    00:57 Okay, the answer should be non-Hodgkin's lymphoma.

    01:00 Question two, which of the following is not typically found in Sjogren's syndrome? Okay, the first two; anti-Ro and anti-La, SSA and SSB, guess what the SS stands for? Both of those can definitely be found in Sjogren's syndrome even if they're not perfectly specific for that condition.

    01:22 Anti-Scl-70 antibody however, that is for diffused cutaneous systemic scleroderma, so that's not associated with Sjogren's syndrome.

    01:33 It's also not in that family of autoimmune conditions that we were talking about before.

    01:37 Rheumatoid factor as we saw in our patient is often positive.

    01:40 And elevated ESR or CRP would not be unusual either.

    01:44 So our answer in this case is definitely number three.

    01:47 And with that, I think we've come to the end.


    About the Lecture

    The lecture Quick Review: Sjögren's Syndrome by Stephen Holt, MD, MS is from the course Connective Tissue Diseases.


    Included Quiz Questions

    1. Sjögren syndrome
    2. Radiation-induced xerostomia
    3. Drug-induced xerostomia
    4. Chronic mucocutaneous candidiasis
    5. Oral leukoplakia

    Author of lecture Quick Review: Sjögren's Syndrome

     Stephen Holt, MD, MS

    Stephen Holt, MD, MS


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    Good lecture
    By Diana B. on 07. September 2020 for Quick Review: Sjögren's Syndrome

    Amazing, live saving; it made Sjorgren so easy and memorable