00:01 Alright, so let's do a quick review. 00:02 I'll ask some questions, feel free to pause the screen, come up with your own answer, and then unpause the screen and we'll see what we came up with. 00:10 First off, all of the following are commonly associated with Sjogren's syndrome except: alright, so we talked about the family of autoimmune diseases with Sjogren's syndrome. 00:24 One of which is definitely Raynaud's phenomenon. 00:27 Again, along with lupus, scleroderma, and others. 00:31 Next stop, Hodgkin's lymphoma, I know we said something about Hodgkin's, it was non-Hodgkin's lymphoma, that's the one that's associated with Sjogren's so that's gonna be our answer and by virtue of it being an incorrect choice. 00:43 Just to round things out, sublingual gland enlargement; definitely a feature of Sjogren's syndrome. 00:49 Oral thrush as we mentioned, by virtue of having a dry mouth and not having saliva. 00:54 And then the dental caries along the same lines. 00:57 Okay, the answer should be non-Hodgkin's lymphoma. 01:00 Question two, which of the following is not typically found in Sjogren's syndrome? Okay, the first two; anti-Ro and anti-La, SSA and SSB, guess what the SS stands for? Both of those can definitely be found in Sjogren's syndrome even if they're not perfectly specific for that condition. 01:22 Anti-Scl-70 antibody however, that is for diffused cutaneous systemic scleroderma, so that's not associated with Sjogren's syndrome. 01:33 It's also not in that family of autoimmune conditions that we were talking about before. 01:37 Rheumatoid factor as we saw in our patient is often positive. 01:40 And elevated ESR or CRP would not be unusual either. 01:44 So our answer in this case is definitely number three. 01:47 And with that, I think we've come to the end.
The lecture Quick Review: Sjögren's Syndrome by Stephen Holt, MD, MS is from the course Connective Tissue Diseases.
A 46-year-old woman presents to the clinic with recurrent oral thrush and dry eyes. Physical examination is significant for scrapable white patches on the tongue, dental caries, bilaterally enlarged parotid glands, and bilateral conjunctival injection. What is the most likely diagnosis?
5 Stars |
|
1 |
4 Stars |
|
0 |
3 Stars |
|
0 |
2 Stars |
|
0 |
1 Star |
|
0 |
Amazing, live saving; it made Sjorgren so easy and memorable