Pancreatic Cancer

by Carlo Raj, MD

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    Pancreatic cancer. Second most common GI cancer. We have cancers such as primary gastric adenocarcinoma. We have colorectal cancer, all being part of GI, and pancreatic cancer, second most common GI cancer. When you say pancreatic cancer, here, we’re referring to adenocarcinoma of the pancreas. Adenocarcinoma. Remember when it comes to the pancreas, you’ll be dividing it into an adenocarcinoma, and your Islet cell tumor cancers. For example, most common, Islet cell tumor, a beta islet cell tumor, a benign cancer called insulinoma. This is adenocarcinoma. Risk factors. Family history plays a big role. Smoking plays a big role. Molecularly, what kind of RAS is associated with pancreatic cancer? Good. K-ras. It is an adenocarcinoma. Endocrine tumor. A cystic tumor. Or a lymphoma. All different types of pancreatic cancers. Our focus in this section will be adenocarcinoma. Remember the endocrine tumors; a beta Islet cell tumor, an alpha Islet cell tumor, a delta Islet cell tumor referring to insulinoma, glucagonoma, somatostatinoma that we’ve discussed all prior. You could have cystic tumors, and perhaps even, lymphomas. Clinical presentation of pancreatic cancer is what you would expect with pancreatitis. Abdominal pain with the radiation to the back. There is going to be weight loss, but you will also find this with chronic pancreatitis. If it’s adenocarcinoma, which actually for you, would be more found or located in the head of the pancreas. Please put the head of the pancreas and jaundice manifestation together. The head of the pancreas is nestled within the second part of the duodenum. If you go on to develop an adenocarcinoma of the head, as it enlarges, it is then going to cause obstruction in the area of the intestine. What happens now? Obstruction. You cannot properly dump out your bile into the second part of the duodenum....

    About the Lecture

    The lecture Pancreatic Cancer by Carlo Raj, MD is from the course Pancreatic and Biliary Tract Diseases.

    Author of lecture Pancreatic Cancer

     Carlo Raj, MD

    Carlo Raj, MD

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