Now, we go to another one. This is large cell.
This is a little scary. And the reason
I say that, you will see. Peripherally located,
so now we have two peripherally located.
The one that is most common. Say
that you are running out of time and you
have really a peripherally located nodule.
One, away from the mediastinum. All you do
real quick, is take a look. Well, is this
a patient that is a female, is a non-smoker?
Adenocarcinoma. I’m sorry, what? Non-smoker,
female, peripherally located, adenocarcinoma.
Go with things that are most common, if you’re
running out of time.
Okay, so with peripherally located nodule.
1: highly anaplastic, undifferentiated. So,
that means that it has a really poor prognosis.
Is less responsive to chemotherapy, removed
surgically. Large anaplastic. Couple of other
things here, histology – pleomorphic and
may secrete βhCG. You hear
a serum test with βhCG, hear about anaplastic. No doubt,
peripherally located, large cell. Adenocarcinoma,
female, non-smoker, peripherally located, then
you know that one. Do not forget about the
in-situ please, in adenocarcinoma.