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00:01 Immunodiagnostics are used to assess patients with suspected immunological conditions. 00:07 Clinical situations in which immune system components are assessed include infection, where we use the term seroconversion to describe a situation where antibodies are produced against specific pathogens. 00:23 So the presence of an antibody against a particular bacterium or virus will indicate that that person is seroconverted. 00:31 We measure immunological parameters in immunodeficiency that can be quantitative measurements or qualitative measurements. 00:41 In allergy, sensitization to allergens is measured. 00:46 In autoimmune disease, autoantibodies and T-cell autoreactivity can be measured. 00:53 And finally in transplantation, HLA matching takes place. 00:58 This was covered in the transplantation lecture.
About the Lecture
The lecture Introduction to Immunodiagnostics by Peter Delves, PhD is from the course Immunodiagnostics.
Included Quiz Questions
Seroconversion refers to?
- The development of antibodies against a specific pathogen.
- The process of plasmapheresis.
- The transfer of specific antibodies into an individual.
- The activation of complement.
- The class switching of antibodies.
Which of the following clinical situations is NOT matched correctly with the immune system component normally assessed?
- Autoimmunity - B cell autoreactivity
- Infection - seroconversion
- Immunodeficiency - qualitative and quantitative measurements
- Transplantation - HLA matching
- Allergens - sensitization
Author of lecture Introduction to Immunodiagnostics
Peter Delves, PhD
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