This lecture is about the control of regulation of breathing.
We have a number of important learning goals to go through.
The first is to identify afferent inputs to the pulmonary system and the respiratory control centers of the brain stem.
In this lecture, we will also discuss how the mechanisms
by which peripheral and central chemoreceptors sense changes in the various blood gases.
And finally, we’ll be able to predict the ventilatory response to a given change in our arterial blood gas.
Okay, let’s get started.
What are the different parameters that we can control to be able to alter ventilation?
We really only have two different things to modulate.
The first is gonna be breathing frequency or how fast one breathes.
The second will be the depth of breath such as the tidal volume.
We have a number of different inputs that will go to the respiratory system.
There are three main classifications; we’ll start off with chemoreceptors.
They are both central chemoreceptors and peripheral chemoreceptors.
There are receptors in the lungs and these will be responsive to things like lung stretch -
and this is very important because if the lungs are overstretched,
they are very fragile environments around the capillaries and the alveoli and they could stretch too much.
There are also irritant receptors in the pulmonary system.
There are specialize sensory fibers known as bronchial C-fibers as well as Juxta-capillary receptors.