Lectures

Treatment of Insulin Overdose – Treatment of Diabetes Mellitus

by Carlo Raj, MD
(1)

Questions about the lecture
My Notes
  • Required.
Save Cancel
    Learning Material 2
    • PDF
      Slides TreatmentOfDiabetesMellitus EndocrinePathology.pdf
    • PDF
      Download Lecture Overview
    Report mistake
    Transcript
    What may then happen if there is insulin overdose? Obviously hypoglycemia, that will be sympathetic systems, tachy, sweating and nausea. The severe overdose may result in massive issues such as convulsions, you are going to have hypomagnesemia, maybe tremors and seizures and hypokalemia therefore resulting in heart issues, cardiac arrest, confusion, bizarre behavior, unconsciousness. The laboratory studies during hypoglycemia are the following. On this table, we will take a look at 3 different conditions. Insulinoma will be our first set of conditions and with this laboratory wise, what we are paying attention to is what is my serum insulin level, what is my serum C peptide level and, well, if at all you were going to find any sulfonylurea, where would you find it, urine or serum? It depends. Our first condition Insulinoma, when would you even see this? Maybe perhaps MEN 1, Insulinoma is a beta islet cell tumor, it is a benign tumor mostly, mostly, one of the rare benign tumors. All the other islet cell tumors tend to be malignant. You can expect there to be lots of insulin and because you are producing this endogenously, you will also find there to be increase in C peptide. So, you have increased insulin, increase in C peptide, but obviously it is nothing to do with sulfonylurea, thus it will be negative. Factitious means exogenous or iatrogenic. Here, you are injecting the patient with tons of insulin or the patient itself or himself or herself is taking quite a bit of insulin for whatever reason. If you are taking insulin from exogenous administration, you will find increase in insulin, but you do not inject C peptide. Thus, you find this to be low. You are injecting insulin, so why in the world would you find sulfonylurea in your serum...

    About the Lecture

    The lecture Treatment of Insulin Overdose – Treatment of Diabetes Mellitus by Carlo Raj, MD is from the course Pancreatic Disease & Diabetes.


    Included Quiz Questions

    1. Metabolic ketoacidosis
    2. Convulsions
    3. Coma
    4. Cardiac arrest
    5. Altered mental status
    1. High serum insulin, high serum C-peptide, absence of sulfonylurea in serum or urine
    2. High serum insulin, low serum C-peptide, presence of sulfonylurea in serum or urine
    3. High serum insulin, low serum C-peptide, absence of sulfonylurea in serum or urine
    4. High serum insulin, high serum C-peptide, presence of sulfonylurea in serum or urine
    5. Low serum insulin, high serum C-peptide, absence of sulfonylurea in serum or urine
    1. Sodium
    2. IV dextrose
    3. IM glucagon
    4. Magnesium
    5. Potassium

    Author of lecture Treatment of Insulin Overdose – Treatment of Diabetes Mellitus

     Carlo Raj, MD

    Carlo Raj, MD


    Customer reviews

    (1)

    5,0 of 5 stars
    5 Stars
    5
    4 Stars
    0
    3 Stars
    0
    2 Stars
    0
    1  Star
    0