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Hypopituitarism

by Carlo Raj, MD
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    Now that we’ve looked at the basics of anterior pituitary, let us now get into the pathology. The first topic here is going to be pituitary insufficiency. Insufficiency, that means that we’re lacking the hormones being released from the anterior pituitary or perhaps the posterior pituitary. Do not forget that. Our first cause or aetiology of our pituitary insufficiency, in fact, is an adenoma. Many a times med students and residents get adenomas and think of it as only being functioning. Do not ever do that, especially with boards. Even though it might be a smaller percentage of adenomas being non-functioning, if you are not paying attention to your patient or question, you get it wrong unnecessarily. So, we have a space-occupying lesion within the pituitary that is causing decreased release or no release of a hormone at all. We’re not quite done. The picture that you’re seeing here, in fact, is the pituitary. The house of your pituitary gland in fact is called the? Good, sella. And the connection between the pituitary and the hypothalamus, as you know and we’ve talked about earlier, is the infundibulum or the stock and the circulation within it is the portal vein. What I would like for you to do is I want you to start thinking of this adenoma growing and growing and growing. Remember, if this is a non-functioning adenoma, a space-space occupying lesion would then knock out a respective hormone coming out of the anterior pituitary or posterior pituitary. But, if this adenoma continuous to grow and let’s say that it compresses the stock, wow, now this is what you need to know. Listen, if that stock has been knocked out for any reason at all, stock compression or stock severance... if you sev-severe the stock then the hormone that...

    About the Lecture

    The lecture Hypopituitarism by Carlo Raj, MD is from the course Pituitary Gland Disorders.


    Included Quiz Questions

    1. GH
    2. FSH
    3. LH
    4. ACTH
    5. TSH
    1. Would cause compression of the portal vein and pituitary ischemia
    2. Would have no effect on hormone release
    3. Would promote release of GH
    4. Would not cause compression or tissue destruction because no hormones are stored or released from this area
    5. Would decrease the release of prolactin
    1. Lymphocytic hypophysitis
    2. Pituitary apoplexy
    3. CNS radiation
    4. Empty sella
    5. Granulomatous
    1. Decreased GH
    2. Decreased gonadotropins
    3. Increased GH
    4. Decreased TSH
    5. Decreased ACTH
    1. ACTH
    2. TSH
    3. GH
    4. GnRH
    5. Prolactin
    1. Gonadotropin
    2. GH
    3. Estrogen
    4. ACTH
    5. TSH

    Author of lecture Hypopituitarism

     Carlo Raj, MD

    Carlo Raj, MD


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