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HER2 Receptor and Bcr-Abl

by Kevin Ahern, PhD
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      Slides HormonesSignalTransduction Biochemistry.pdf
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    About the Lecture

    The lecture HER2 Receptor and Bcr-Abl by Kevin Ahern, PhD is from the course Hormones and Signal Transduction. It contains the following chapters:

    • HER2 Receptor
    • Other Mutations – Bcr-Abl

    Included Quiz Questions

    1. It is inhibited by Trastuzumab/Herceptin.
    2. It requires EGF to bind to it.
    3. It stimulates cells to divide when it is a monomer.
    4. All of the answers are true.
    5. None of the answers are true.
    1. It creates a tyrosine kinase that binds Gleevec differently from other tyrosine kinases.
    2. It is a tyrosine kinase that is more active than the Abl protein unmutated.
    3. It is treated with Gleevec, a GTPase inhibitor.
    4. All of the answers are true.
    5. None of the answers are true.

    Author of lecture HER2 Receptor and Bcr-Abl

     Kevin Ahern, PhD

    Kevin Ahern, PhD


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