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Hepatitis C

by Carlo Raj, MD
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    Hepatitis C It's an a RNA virus. Incubation period: 2-26 weeks. These are the type of viral hepatitides in which you worry about chronicity. 40-80% of your cases, whenever you have hepatitis c ocurring and it going to chronicity, what are you worried about? Big time! liver cancer. hepatitis B back in the 70's and 80's was an absolute endemic. Since then, things have subsided quite a bit. And in pharmacology management, you should definitely know about hepatitis C, genotype 1. You focus on genotype 1. Because we can now treat hepatitis C. Not just treat cure a patient between 8-12 weeks with genotype 1. This is new information. This is research that is now thrown into clinical application and translating into patients that are completely cured. Interferon-free therapy. Amazing. Some of the prognosis you should know of, include *letopasphere Sofosbuvir the combination of the two without interferon. Most common reason for liver transplantation because of chronicity. Your liver dies... 4 million cases still in the U.S. Alcohol abuse accelerates the disease progression as you could imagine. Risk factors. Transfusions prior to 1990. At this point, we're good. I mean to say we have enough check and balances. You walk in and there is transfusion that is required. There is going to be a nurse that is always there with you to check things off. to make sure that you are not passing hepatitis c into your patient. Avid drug users, intranasal cocaine use. High risk sexual behavior or tattooing and hemodialysis. Keep in mind with tattoos. That you may then pass on hepatitis c. Clinical presentation. Acute disease usually asymptomatic. At some point, they may then show jaundice. Incidental findings on routine physicals. Meaning to say, the patient is seem so asymptomatic they might feel a little bit of...

    About the Lecture

    The lecture Hepatitis C by Carlo Raj, MD is from the course Cirrhosis – Liver Diseases.


    Included Quiz Questions

    1. Genotype 1
    2. Genotype 2
    3. Genotype 3
    4. Genotype 4
    5. Genotype 5
    1. Poor sanitation
    2. Hemophiliac who was diagnosed before 1990
    3. Intranasal cocaine use
    4. Unclean methods of tattooing
    5. Hemodialysis
    1. Mixed essential cryoglobinuria
    2. Porphyria cutanea tarda
    3. Membranous glomerulonephritis
    4. Erythema nodosum
    5. B cell lymphoma
    1. Hyperviscosity due to cryoglobulins
    2. Hyperviscosity due to complement
    3. Hyperviscosity due to increased immunoglobulins
    4. Hyperviscosity due to increased leucocyte count
    5. Hyperviscosity due to drugs used to treat Hepatitis C
    1. AntiHCV by ELISA
    2. Anti-HCV by PCR
    3. HCV DNA by PCR
    4. HCV DNA by ELISA
    5. Serum transaminases
    1. Alcohol
    2. Smoking
    3. Gall stones
    4. Steatorrhea
    5. Pregnancy
    1. Hepatocellular carcinoma
    2. Pan sclerosing cholangitis
    3. Hepatic adenoma
    4. Focal nodular hyperplasia

    Author of lecture Hepatitis C

     Carlo Raj, MD

    Carlo Raj, MD


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    update
    By QUANHUI Z. on 04. December 2016 for Hepatitis C

    Since December 2013, Several DAA drugs were approved by FDA. So you can update this lecture.