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Hepatitis A

by Carlo Raj, MD
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    00:01 Viral hepatitis.

    00:02 We’ll go through the important causes of viral hepatitis or hepatites.

    00:08 In general, self-limited acute – A, acute, give yourself an example – viral hepatitis A.

    00:17 E, we’ll talk about in a little bit.

    00:19 And then we'll talk about viruses that usually affect the liver in an acute nature – EBV, CMV, HSV.

    00:28 Chronic hepatitis, more so dealing with your B, C and D.

    00:39 Begin by looking at our hepatitis A.

    00:42 Acute, A.

    00:44 Transmission: feco-oral transmission.

    00:47 Incubation period, about two to six weeks.

    00:50 Presents with nausea and vomiting – n/v.

    00:54 And think about where your liver is, RUQ, right upper quadrant pain, with jaundice.

    00:59 Remember that jaundice, mixed picture.

    01:01 All depends as to how much damage has taken place to liver.

    01:04 What kind of clues are they going to give you on your board, so that you know as to – wow, liver might be affected? AS, ALT transaminases.

    01:13 In viral, it would be more ALT.

    01:16 Can cause severe disease in elderly or patients with pre-existing liver disease.

    01:22 Does not – I repeat, does not lead to chronic hepatitis, but can have relapsing course.

    01:28 A – hepatitis A – you should be thinking A, acute, not so much chronic.

    01:34 Diagnosed by anti-HAV IgM antibody.

    01:43 Prevention of hepatitis A.

    01:44 Vaccination recommended for travelers to endemic areas.

    01:49 Military workers. IV drug abusers or IV drug users.

    01:55 Homosexuals, remember feco-oral is your route.

    02:00 Patients with chronic liver disease.

    02:02 And the reason for that, remember, A will not cause chronicity.

    02:06 However, if there's a pre-existing liver disease, then hepatitis A will only make it worse and allow the patient to go into fulminant hepatitis.

    02:16 Vaccinate, close contact of a case in which maybe perhaps there is something with close encounters that might have taken place.

    02:26 For example, think about prisoners and convicts.

    02:29 Immunoglobulin useful for passive immunity for suspected exposure if used within two weeks.

    02:36 Prevention becomes important here with hepatitis A.

    02:39 This is where your focus should be, approximately two weeks.


    About the Lecture

    The lecture Hepatitis A by Carlo Raj, MD is from the course Cirrhosis – Liver Diseases.


    Included Quiz Questions

    1. Hepatitis B
    2. Hepatitis A
    3. Hepatitis E
    4. CMV hepatitis
    5. EBV hepatitis
    1. Hepatitis E commonly occurs in pregnant women.
    2. The feco-oral route is the mode of transmission of Hepatitis A.
    3. The incubation period of Hepatitis A virus is 2-6 weeks.
    4. Hepatitis A-induced acute hepatitis is diagnosed by Anti-HAV IgM antibodies.
    5. Hepatitis A can have episodes of relapse and remission.
    1. A patient with relapse of Hepatitis A.
    2. A patient traveling to endemic areas of hepatitis A
    3. A patient with chronic liver disease
    4. Homosexual men
    5. Close contacts of the index case

    Author of lecture Hepatitis A

     Carlo Raj, MD

    Carlo Raj, MD


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