by Carlo Raj, MD

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    The topic begins here with the gynecomastia. With gynecomastia in pharmacology, make sure that you are familiar with the list medications that are responsible for developing gynecomastia. There are mnemonics out there. If I were you, I would Google it to be honest and know the list. Our topic will begin into endocrine disorders that result in gynecomastia, actual pathology. Hyperthyroidism could be a possibility. Primary hypogonadism especially if we’re dealing with a condition called Klinefelter which we will talk about in great detail and you should be extremely familiar with. A patient who has a genotype of XXY might also have pragmatism, jaw, masculine-like and gynecomastia or hormone-secreting tumors. For example, if you have a hormone such as estrogen that’s being released in a male, with a tumor known as your let’s say, the granulosa cell tumor, granulosa cell and producing too much estrogen resulting in gynecomastia or perhaps even hCG with the choriocarcinoma. Chronic systemic illnesses resulting in gynecomastia. Renal diseases and hepatic diseases at times are associated with gynecomastia. Marijuana, look for that quite a bit especially in today’s society where access to marijuana, of course is becoming easier and easier. Idiopathic. Now, if gynecomastia is observed in your patient, consider malignancy if the following: unilateral, ulcerative, not concentric with nipple. These are definite types of characteristics of gynecomastia that raises concern as to whether or not malignancy is involved. Oftentimes with gynecomastia, you might find bloody discharge or perhaps even axillary lymphadenopathy. Keep in mind though with axillary lymphadenopathy if it’s a female. Remember we were dealing with the male here but gynecomastia could be found in both patients. And if it’s axillary lymphadenopathy, maybe perhaps even breast cancer. Lab wise, renal hepatic function, important. Chronic systemic illness, renal failure, big time important. Liver failure. Testosterone...

    About the Lecture

    The lecture Gynecomastia by Carlo Raj, MD is from the course Reproductive Hormone Disorders.

    Included Quiz Questions

    1. Seminoma
    2. Hyperthyroidism
    3. Primary hypogonadism
    4. Granulosa cell tumors
    5. Choriocarcinoma
    1. Bilateral
    2. Axillary LN enlargement
    3. Nonconcentric enlargement with nipples
    4. Ulcers
    5. Bloody discharge
    1. ACTH
    2. LH/FSH
    3. Testosterone
    4. Liver function test
    5. TSH

    Author of lecture Gynecomastia

     Carlo Raj, MD

    Carlo Raj, MD

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