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Germinal Center – Lymphocyte Activation

by Peter Delves, PhD
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    About the Lecture

    The lecture Germinal Center – Lymphocyte Activation by Peter Delves, PhD is from the course Adaptive Immune System. It contains the following chapters:

    • A Closer Look at the Germinal Center

    Included Quiz Questions

    1. T follicular helper (Tfh) cells
    2. T-cell somatic hypermutation
    3. Antibody secretion
    4. Follicular dendritic cell activation of T cells
    5. T-cell receptor gene rearrangement
    1. B cell binds Helper T cell to enter Dark Zone of germinal center, B cells proliferate and move to Light Zone, B cells undergo somatic mutation and isotype switching, differentiation and migration out of the germinal center as Memory B cell or Plasma cell
    2. B cell binds Helper T cell to enter Light Zone of germinal center, B cells proliferate and move to Dark Zone, B cells undergo somatic mutation and isotype switching, differentiation and migration out of the germinal center as Memory B cell or Plasma cell
    3. B cell enters Dark Zone of germinal center, B cells proliferate and move to Light Zone, differentiation and migration out of the germinal center as Memory B cell or Plasma cell, B cells undergo somatic mutation and isotype switching
    4. B cell binds Helper T cell to enter Dark Zone of germinal center, B cells undergo somatic mutation and isotype switching in the Light Zone, differentiation and migration out of the germinal center as Memory B cell or Plasma cell
    5. B cell enters Dark Zone of germinal center, B cells proliferate and move to Light Zone, B cells undergo somatic mutation and isotype switching, differentiation and migration out of the germinal center as Dendritic cell or Helper T cell

    Author of lecture Germinal Center – Lymphocyte Activation

     Peter Delves, PhD

    Peter Delves, PhD


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