Lectures

Genetic Susceptibility to Autoimmune Diseases and Mechanisms – Autoimmune Diseases

by Peter Delves, PhD
(1)

Questions about the lecture
My Notes
  • Required.
Save Cancel
    Learning Material 2
    • PDF
      Slides Autoimmune Disease.pdf
    • PDF
      Download Lecture Overview
    Report mistake

    About the Lecture

    The lecture Genetic Susceptibility to Autoimmune Diseases and Mechanisms – Autoimmune Diseases by Peter Delves, PhD is from the course Hypersensitivity and Autoimmune Disease. It contains the following chapters:

    • Mechanisms of Autoimmune Disease
    • MHC Associations in Autoimmune Disease
    • Role of Infection in the Development of Autoimmune Disease

    Included Quiz Questions

    1. HLA-B27
    2. HLA-B2
    3. HLA-B7
    4. HLA-B8
    5. HLA-B72
    1. Tissue injury which causes self presenting APCs and self-reactive effector lymphocytes
    2. Accumulation of APCs around tissue effected by stimuli
    3. Lymphocytes that are reactive to environmental elements which mutate and become autoreactive
    4. Changes in morphology of MHC leading to self presenting APCs and self-reactive effector lymphocytes
    5. Changes in genetic expression of tumor suppressor genes
    1. IL-10
    2. CTLA4
    3. IL-2
    4. BLK
    5. MHC
    1. Type I Diabetes
    2. Hasimoto's Disease
    3. Myasthenia Gravis
    4. Ankylosing spondylitis
    5. Rheumatoid arthritis
    1. A sharing of structures or sequences between self antigens and microbial antigens, leading to autoimmunity
    2. A B cell mediated reaction which results in production of identical autoantibodies
    3. Destruction of healthy tissue cells because they resemble damaged tissue cells
    4. Autoimmune complexes that mimic antigens and deposit in lymphocytes
    5. Inability to clear antigens which are deposited in damaged tissues, leading to tissue destruction

    Author of lecture Genetic Susceptibility to Autoimmune Diseases and Mechanisms – Autoimmune Diseases

     Peter Delves, PhD

    Peter Delves, PhD


    Customer reviews

    (1)

    5,0 of 5 stars
    5 Stars
    5
    4 Stars
    0
    3 Stars
    0
    2 Stars
    0
    1  Star
    0