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Gene Expression Control – Metabolic Control of Enzyme Activity

by Kevin Ahern, PhD
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    About the Lecture

    The lecture Gene Expression Control – Metabolic Control of Enzyme Activity by Kevin Ahern, PhD is from the course Metabolic Control.


    Included Quiz Questions

    1. Nucleotide
    2. Transcriptional
    3. RNA stability
    4. Translational
    1. HIF-1
    2. HIF-2
    3. GLUT1
    4. GLUT2
    5. Two transcription factors called GLUT1 and GLUT3
    1. The HIF-1 factor helps the cell to combat with toxic conditions originated due to higher oxygen levels
    2. Under hypoxia condition, the regular cells, as well as cancer cells, synthesize the transcription factor called as HIF-1
    3. HIF-1 factor favors elevated levels of expression of the seven enzymes of the glycolysis pathway during hypoxia condition
    4. HIF-1 factor binds to the particular class of genes in the DNA which help in the survival of cell at low oxygen concentrations
    5. The transcription factor HIF-1 helps in the movement of glucose to the interior of the cell by favoring the formation of GLUT1 and GLUT3 proteins
    1. Controlling the process of transcription and hence synthesis of a specific mRNA and protein molecules
    2. Controlling the permeabilities of the cell membrane and mitochondrial membrane for water
    3. Controlling the fluidity of cell membrane by regulating the ion movement
    4. Controlling the amounts of energy in the form of ATP and GTP
    5. Controlling the amounts of rRNA and tRNA to regulate

    Author of lecture Gene Expression Control – Metabolic Control of Enzyme Activity

     Kevin Ahern, PhD

    Kevin Ahern, PhD


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