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The Endocrine Pancreas.
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We are here to talk about a lot
of interesting things today.
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We may even have a little
bit of fun.
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We'll do insulin and glucagon.
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The important thing to think
about when you're going through
the exocrine pancreas, is that
this was involve for secreting
enzymes for the GI track.
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Now we're going to talk
about endocrine pancreas.
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This will then put
substances in the blood,
they'll travel around
the whole body
and cause a systemic effect.
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So the endocrine pancreas is
what we're talk about today.
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There are 4 substances that
are produced in the endocrine
pancreas that is
glucagon, insulin,
somatostasin and
pancreatic polypeptide.
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But it is glucagon and insulin
that we're going to be concerned
ourselves most.
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Because this is what is going
to control
our blood glucose levels.
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And blood glucose is one of
the most important things
we can regulate in our body.
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The other thing we are going
to bring about this kind
of scenario that it is that there are different cells
for each one of these each substances.
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So beta cells, those we'll be
involved in insulin secretion.
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Alpha cells those are
born for glucagon.
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The other thing that's
interesting is that blood flow
pattern that we have
throughrout the pancreas,
specially in these islets are
from the inside of the cell
towards the outside of the cell.
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Therefore, blood can pass
by multiple cell types.
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And that is helpful for two
of the other cell types,
somatostatin polyide,
pancreatic polypeptide.
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Because these cells may be able
to regulate
some of the other cells specially somatostatin
which is released
by the delta cells.
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As you go through this process,
think about which one of these
hormones are regulating
each other.
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And how this blood flow
pattern might be helpful.