Endemic Mycoses: Learning Outcomes

by Vincent Racaniello, PhD

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    00:01 So after listening to our discussion of endemic mycoses, I hope you can name the fungi that we've talked about, that cause endemic mycoses. You should be familiar with the pathogenesis and the epidemiology of histoplasmosis and coccidioidomycosis, and you should know which drugs can be used treat these endemic mycoses.

    00:22 Thanks for listening and see you next time.

    About the Lecture

    The lecture Endemic Mycoses: Learning Outcomes by Vincent Racaniello, PhD is from the course Fungi.

    Included Quiz Questions

    1. A person with several used ash trays scattered throughout their home
    2. A construction worker helping demolish an old bank
    3. A chicken farmer
    4. A spelunker who maps caves for a local park
    5. A person who has made a hobby of feeding local pigeons
    1. Having CD4 positive T-helper lymphocytes
    2. Having COPD
    3. Having AIDS
    4. Being an active smoker
    5. Being immunosuppressed
    1. Using enzyme linked immunosorbent assays (ELISA) to grow the active fungus from a urine or serum sample
    2. Analyzing clinical specimens such as sputum, blood, tissue samples or other body fluids
    3. Analyzing samples of bone marrow, liver, lung or lymph
    4. Using enzyme linked immunosorbent assays (ELISA) to look for the fungal antigen
    5. Looking for the polysaccharide antigen from the cell wall of the fungus in a urine or serum sample
    1. Southwestern United States
    2. Northeastern United States
    3. Sub-Saharan Africa
    4. West Africa
    5. Eastern Europe
    1. With both fungi, spores are inhaled into the lungs and begin infection there
    2. Both are carried in bat and bird feces
    3. Both fungal infections can be transferred through coughing and sneezing from an infected individual
    4. With both fungi, the presence of functioning macrophages is an essential requirement for growth
    5. Both fungi are endemic to the same geographic area
    1. A short term treatment option is to combine fluconazole and amphotericin B
    2. 1 to 2 years of treatment is required
    3. Treatment is typically done with itraconazole or fluconazole
    4. More severe infections require amphotericin B as a part of treatment
    5. Meningitis caused by coccidia requires treatment with fluconazole and that must continue for the rest of the patient's life

    Author of lecture Endemic Mycoses: Learning Outcomes

     Vincent Racaniello, PhD

    Vincent Racaniello, PhD

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