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Drug Schedules and Controlled Substances – Drugs of Abuse

by Pravin Shukle, MD
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    How do we classify illicit medications or medication with high risk of potential? The FDA has a four point classification system, one being the worst, and four being not so bad. So, we call the worst drug schedule I drugs. So, schedule I drugs have no medical use at all. And they have a very high addiction potential. So, those are drugs like heroin, LSD, mescaline and all of the others that are listed there. Grade II or schedule II drugs are drugs that do have a medicinal use, but they also have a high addiction potential. So, we try not to use these drugs as much as possible. These includes the amphetamines, so the only amphetamine that we're using clinically is, sometimes we use ketamine in anesthesia but otherwise, we don't use it outside of that limited use. Cocaine, we sometimes use clinically, with people who have severe nose bleed. So, I remember when I was in pharmacy school, we had to make a cocaine paste. And I remember being very nervous about inhaling any of the product. So, it is used. We do use cocaine paste in nose bleed. But it's not as commonly used, and it's not something that we often encourage its use. Methylphenidate, short acting barbiturates and strong opioids are also used. A good example of a strong opioid that's used in clinical practice is fentanyl which has now become one of the most abused opioid in the market today. Now, the schedule III drugs have a lot of medical use. There is a moderate abuse potential with them. So, these are the anabolic steroids that I had mentioned earlier, barbiturates, and sometimes moderate opioid agonists. The class IV drugs are medically use and there's a low abuse potential. So, these are most of the...

    About the Lecture

    The lecture Drug Schedules and Controlled Substances – Drugs of Abuse by Pravin Shukle, MD is from the course Toxicology.


    Included Quiz Questions

    1. LSD
    2. Benzodiazepines
    3. Ketamine
    4. Dronabinol
    5. Anabolic steroids

    Author of lecture Drug Schedules and Controlled Substances – Drugs of Abuse

     Pravin Shukle, MD

    Pravin Shukle, MD


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