00:00 Take a look at dermatomyositis or polymyositis. 00:03 I want you to focus upon dermato- and that to you of course means skin. 00:08 When this type of autoimmune disease is kicking in, Understand that the skin is going to be the first thing to be affected You've heard of heliotrope rash around the eye, periorbital. 00:19 You've heard of Graafian lesions, and that's over your knuckles. 00:22 So those are rashes that the patient might then be describing to you over the knuckles and so forth. 00:27 And then what do you think is involved? Good, myo- means muscle. 00:32 So dermatomyositis, autoimmune diseases once again, what's going on here? Could the lung be involved? Very much so. 00:39 Whenever you think about autoimmune diseases, then who is your gender most likely? Females. 00:45 also seen with, well, who's to know the antibody antisynthetase antibodies with dermatomyositis. 00:53 Frequent involvement of the skin, I gave you a couple there, heliotrope and I gave you Graafian lesions in muscles associated with the lung disease, that should clue you in. 01:03 Now here we go again. 01:05 If you do not have much fibrosis, think of this as being a continuum Continuum of what? The amount of fibrosis that you're laying down. 01:13 If it is not much, you then refer to it as being nonspecific interstitial pneumonitis What's that mean? Oh, look I don't find many fibroblast. 01:22 So once again from histo, make sure that you are clearly, clearly familiar with what a fibroblast looks like. 01:31 If you have increased deposition of fibrosis, uh oh we have usual interstitial pneumonitis and pathologically or excuse me, clinically we then call this or diagnose this idiopathic pulmonary fibrosis. 01:44 High association with occult malignancy, and that is unfortunate.
The lecture Dermatomyositis and Polymyositis by Carlo Raj, MD is from the course Restrictive Lung Disease.
What autoantibody is commonly associated with dermatomyositis?
Which of the following is strongly associated with dermatomyositis/polymyositis?
Which of the following autoimmune diseases is least likely to present with nonspecific interstitial pneumonia?
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The title says dermatomyositis and polymyositis. HE DIDNT EXPLAIN OR BRING UP POLYMYOSITIS. this lecture series is rushed and done poorly.