Take a look at dermatomyositis
I want you to focus upon dermato- and
that to you of course means skin.
When this type of autoimmune
disease is kicking in,
Understand that the skin is going to
be the first thing to be affected
You've heard of heliotrope rash
around the eye, periorbital.
You've heard of Graafian lesions,
and that's over your knuckles.
So those are rashes that
the patient might then be
describing to you over the
knuckles and so forth.
And then what do you
think is involved?
Good, myo- means muscle.
autoimmune diseases once
again, what's going on here?
Could the lung be involved?
Very much so.
Whenever you think about
then who is your
gender most likely?
also seen with, well, who's
to know the antibody
Frequent involvement of the skin,
I gave you a couple there, heliotrope
and I gave you Graafian lesions
in muscles associated with the lung
disease, that should clue you in.
Now here we go again.
If you do not have much fibrosis,
think of this as being a continuum
Continuum of what?
The amount of fibrosis
that you're laying down.
If it is not much, you then refer to it as
being nonspecific interstitial pneumonitis
What's that mean?
Oh, look I don't find many fibroblast.
So once again from histo, make
sure that you are clearly, clearly
familiar with what a
fibroblast looks like.
If you have increased
deposition of fibrosis,
uh oh we have usual
and pathologically or excuse
me, clinically we then call this
or diagnose this idiopathic
High association with occult
malignancy, and that is unfortunate.