Colon Cancer: Risk Factors, Diagnosis & Treatment

by Carlo Raj, MD

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    00:01 Middle aged men, PCR analysis for bacterial DNA is confirmatory.

    00:06 Diarrhea, abdominal pain, arthritis, neurologic deficit, lymphadenopathy, remember this is a bacterial disease.

    00:14 Diagnosis here would include periodic acid schiff where you would find these granules in your macrophages and the management for this would be antibiotics such as cotrimoxazole.

    00:31 Tropical Sprue, as the name implies, these would be tropical regions, associated with megaloblastic anemia.

    00:38 Tropical Sprue, some would say that it is infectious but exact cause and etiology is pretty much unknown, but then the reason for the folic deficiency resulting in megablastic anemia, that´s the part they were unclear about.

    00:51 So the most important symptom is something that pretty much remains a mystery or idiopathic.

    00:57 Here, the pathology similar to Celiac Sprue, but has nothing to do with gluten.

    01:05 So you have three conditions here in which you wanna keep in mind when you´re dealing with Celiac just to make sure.

    01:10 Celiac disease, we know everything about.

    01:13 Next, we take a look at Whipple but that´s your Tropheryma, that´s your bacteria periodic acid schiff. Yes, diarrhea there as well.

    01:21 Tropical Sprue, here once again, it seems as though that it destroys the intestine, megaloblastic anemia, unknown cause maybe perhaps infectious because of this, tetracycline antibiotic but more importantly, the folate.

    01:36 Not the B12 deficiency here that you find in Tropical Sprue.

    About the Lecture

    The lecture Colon Cancer: Risk Factors, Diagnosis & Treatment by Carlo Raj, MD is from the course Small and Large Intestine Diseases. It contains the following chapters:

    • Colon Cancer - Clinical Presentation
    • Colon Cancer - Diagnosis
    • Colon Cancer - Prognosis, Treatment & Prevention

    Included Quiz Questions

    1. Males - lung cancer > prostate cancer > Colon cancer Females- Lung cancer > breast cancer > colon cancer
    2. Males - Colon cancer > prostate cancer > Lung cancer Females - Colon cancer > Breast cancer > lung cancer
    3. Males - Prostate cancer > colon cancer > lung cancer Females - Breast cancer > colon cancer > lung cancer
    4. Males - Lung cancer > Prostate cancer > Gastric cancer Females - lung cancer > Breast cancer > Cervical cancer
    5. Males - Lung cancer > Gastric cancer > Prostate cancer Females - Lung cancer > Cervical cancer > Prostate cancer
    1. Smoking
    2. Low fiber diet
    3. Long-standing inflammatory bowel disease
    4. Hereditary polyposis syndrome
    5. Colorectal adenoma
    1. Colonoscopy
    2. Proctoscopy
    3. Ultrasound
    4. X-ray abdomen
    5. Sigmoidoscopy
    1. CEA
    2. Inhibin
    3. Beta HCG
    4. CA 19-9
    5. CA-125
    1. K- ras
    2. RET
    3. Src
    4. Wnt
    5. Myc
    1. Liver
    2. Bone marrow
    3. Breast
    4. Brain
    5. Spleen
    1. Regional lymph node involvement
    2. Involvement of limited to the submucosa
    3. Involvement beyond the submucosa without lymph node involvement
    4. Distant metastasis to liver
    5. Distant metastasis to brain
    1. Screening of colon cancer in FAP disease starts after 50 years of age.
    2. Screening of colon cancer starts from the age of 50 years.
    3. Screening for colon cancer is by colonoscopy.
    4. Screening for colon cancer in a patient who has a first degree relative with colon cancer is at 40 years or 10 years prior to the first degree relative.
    5. Screening for colon cancer must begin at 8 years of colon inflammatory bowel disease duration.

    Author of lecture Colon Cancer: Risk Factors, Diagnosis & Treatment

     Carlo Raj, MD

    Carlo Raj, MD

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