00:01
Let?s take a look at the anterior pituitary.
00:03
Now, what we have here is a structure of the
anterior pituitary and all the different hormones
that come out of it, but it?s not important
that you memorize the locations of it.
00:15
But, what I do want you to pay attention to
would be specifically these melanotropes and
lactotropes.
00:22
The reason for that is because in terms of
its origination of the hormones from the anterior
pituitary, which by the way develops embryologically
from the Rathke?s Pouch and that is something
that you want to keep in mind.
00:36
Absence of the Rathke?s Pouch, you end up
losing or do not develop the anterior pituitary.
00:43
But, the somatotropes and the lactotropes
become important and when we get to our discussion
of somatotropes, we are not and you are not
going to confuse that with somatostatin, even
though the prefix might sound similar.
01:00
Keep that in mind.
01:01
Also, when we come to histology, it?s important
that you pay attention to the type of staining
method that takes place.
01:10
And by that, I mean the two major staining
methods include acidophils and basophils
or acidophilic and basophilic.
01:20
And I will show you picture upcoming in which
you notice here in the picture, that S and
L are put together.
01:29
And they?re in the same vicinity.
01:31
And so, therefore, the type of stain that
they didn?t take up would be, once again,
similar versus all of the others that then
have a different type of staining and that
is then referred to as being basophilic.
01:45
And what does that mean?
Well, when you say acidophilic, as we shall
see, the colour of it or the staining of it
will then be rather pinkish. Whereas if it's basophilic,
and you've seen it over and over again.
01:59
That would be rather dark, wouldn't it?
Dark blue purple is what you're thinking of.
02:04
Somatotropes and lactotropes is what you?re
paying attention to and after you compartmentalize
this, at some point in time, understand the
anterior pituitary is going to completely
mix all this up.
02:16
And so, therefore, it might look something
like this.
02:20
And what this image is pointing to is... are
your pink acidophils.
02:25
And if I were you, I?d focus upon these
two, the S and the L, and the S referring
to, not somatostatin, but somatotropines.
02:35
Now, where this becomes important is, if I
were you and reading a stem of a question,
it?s a physio or anatomy or embryologic
question, whenever you see the suffix -tropic
or
-trop, it means promotion, promoting.
02:50
So, whenever you hear the word tropic, it
always means releasing versus inhibiting.
02:58
And so, therefore, somatotropes would be those
that then give rise to growth hormone whereas
your lactotropes will be prolactin and by
that, you should be thinking prolactin?s
responsible for milk synthesis, right?
So, therefore, it would be a contributing
factor when it comes to breast-feeding and
milk.
03:19
Milk referring to lacto, if that helps you.
03:24
Whereas all of the rest would be dark, purplish,
basophilic and by that, I mean rest of the
anterior pituitary hormones.
03:33
Remember please, that in this section, all
that we?re referring to is the anterior
pituitary.
03:39
We already had our discussion when dealing
with the posterior pituitary and its clinical
applications.