Interpretation of Serum Calcium and Serum Phosphate Levels

00:02 Simplified Calcium/Phosphate interpretation.

00:05 Low Vitamin D action, low calcium and we have low phosphate, unless renal failure.

00:13 I’ve emphasized that so many times now.

00:16 Whenever you have calcium imbalance, you’re always going to look for renal status, always.

00:23 It changes the entire complexity or complexion of the pathology.

00:28 If it’s high Vitamin D action, the opposite would be true.

00:33 If it’s low PTH action, why? Well, maybe the hyperparathyr-... the parathyroids have been lost resulting in low PTH action.

00:44 You would expect there would be low calcium and high phosphate.

00:48 If there’s high PTH or PTHrp and with this, we’ve talked about with primary hyperparathyroidism or secondary hyperparathyroidism, once again, the big exception here, we expect your calcium to be high, your phosphate will be low because PTH gets rid of your phosphate, unless renal failure where the phosphate will be elevated.

01:13 Bottom line, calcium and phosphate tend to deviate together, both up or down, in Vitamin D derangements whereas the deviation or the changes between calcium and phosphate will be the opposite when it comes to parathyroid pathologies, generally.

01:34 Exception, chronic… a big exception, chronic renal failure.